U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    CG3061 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41707, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CG3061provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0038195
    Locus tag
    Dmel_CG3061
    See related
    AllianceGenome:FB:FBgn0038195
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG3061
    Summary
    Predicted to enable Hsp70 protein binding activity. Predicted to be involved in cellular response to misfolded protein and chaperone cofactor-dependent protein refolding. Located in endomembrane system. Is expressed in adult head and organism. Orthologous to several human genes including DNAJB12 (DnaJ heat shock protein family (Hsp40) member B12). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CG3061 in Genome Data Viewer
    Location:
    88A4-88A4; 3-54 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (14032371..14035041)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (9858093..9860763)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR43460 Neighboring gene roadkill Neighboring gene transfer RNA:Serine-GCT 2-2 Neighboring gene Cytochrome P450 6d5 Neighboring gene uncharacterized protein Neighboring gene forkhead box, sub-group O

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Discovery of insect and human dengue virus host factors. Sessions OM, et al. Nature, 2009 Apr 23. PMID 19396146, Free PMC Article
    2. The Cyclically Seasonal Drosophila subobscura Inversion O(7) Originated From Fragile Genomic Sites and Relocated Immunity and Metabolic Genes. Karageorgiou C, et al. Front Genet, 2020. PMID 33193649, Free PMC Article
    3. Life extension in Drosophila by feeding a drug. Kang HL, et al. Proc Natl Acad Sci U S A, 2002 Jan 22. PMID 11792861, Free PMC Article
    4. RNAi-Mediated Reverse Genetic Screen Identified Drosophila Chaperones Regulating Eye and Neuromuscular Junction Morphology. Raut S, et al. G3 (Bethesda), 2017 Jul 5. PMID 28500055, Free PMC Article
    5. Mettl3-dependent m(6)A modification attenuates the brain stress response in Drosophila. Perlegos AE, et al. Nat Commun, 2022 Sep 14. PMID 36104353, Free PMC Article

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables Hsp70 protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in cellular response to misfolded protein IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in chaperone cofactor-dependent protein refolding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in endomembrane system HDA PubMed 
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    uncharacterized protein
    Names
    CG3061-PA
    dnaJ like2

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      14032371..14035041
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142071.3 → NP_650328.1  uncharacterized protein Dmel_CG3061 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650328.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VFP0
      Related
      FBpp0082332
      Conserved Domains (3) summary
      COG0484
      Location:105 → 224
      DnaJ; DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]
      pfam00226
      Location:106 → 167
      DnaJ; DnaJ domain
      pfam09320
      Location:269 → 366
      DUF1977; Domain of unknown function (DUF1977)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VFP0 Q9VFP0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools