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    CG13654 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43028, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG13654provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039290
    Locus tag
    Dmel_CG13654
    See related
    AllianceGenome:FB:FBgn0039290
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG13654
    Summary
    Predicted to be located in membrane. Is expressed in adult head. Orthologous to human PGAP6 (post-GPI attachment to proteins 6) and TMEM8B (transmembrane protein 8B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG13654 in Genome Data Viewer
    Location:
    96C4-96C5; 3-87 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (25199818..25214255)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (21025540..21039977)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene lost boys Neighboring gene distal antenna Neighboring gene uncharacterized protein Neighboring gene Cadherin 96Ca Neighboring gene SAYSVFN motif domain containing 1 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Unpredictable Effects of the Genetic Background of Transgenic Lines in Physiological Quantitative Traits. Evangelou A, et al. G3 (Bethesda), 2019 Nov 5. PMID 31540975, Free PMC Article
    2. Population- and sex-biased gene expression in the excretion organs of Drosophila melanogaster. Huylmans AK, et al. G3 (Bethesda), 2014 Sep 22. PMID 25246242, Free PMC Article
    3. Loss of the endoplasmic reticulum protein Tmem208 affects cell polarity, development, and viability. Dutta D, et al. Proc Natl Acad Sci U S A, 2024 Feb 27. PMID 38381787, Free PMC Article
    4. GlycoFly: a database of Drosophila N-linked glycoproteins identified using SPEG--MS techniques. Baycin-Hizal D, et al. J Proteome Res, 2011 Jun 3. PMID 21480662
    5. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG13654-PA
    CG13654-PB
    CG13654-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      25199818..25214255
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_143093.3 → NP_651350.2  uncharacterized protein Dmel_CG13654, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651350.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VBW1
      Conserved Domains (1) summary
      pfam12036
      Location:804 → 973
      DUF3522; Protein of unknown function (DUF3522)

    2. NM_001300594.1 → NP_001287523.1  uncharacterized protein Dmel_CG13654, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287523.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4LIM4
      Conserved Domains (1) summary
      pfam12036
      Location:778 → 947
      DUF3522; Protein of unknown function (DUF3522)

    3. NM_001300593.1 → NP_001287522.1  uncharacterized protein Dmel_CG13654, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287522.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4LIM4
      Conserved Domains (1) summary
      pfam12036
      Location:778 → 947
      DUF3522; Protein of unknown function (DUF3522)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4LIM4 A0A0B4LIM4
    Q9VBW1 Q9VBW1

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