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    Yif1 Yip1-interacting factor 1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43217, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Yif1provided by FlyBase
    Official Full Name
    Yip1-interacting factor 1provided by FlyBase
    Primary source
    FLYBASE:FBgn0288631
    Locus tag
    Dmel_CG5484
    See related
    AllianceGenome:FB:FBgn0288631
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0118547.366; CG5484; COP; Dmel\CG5484; doc
    Summary
    Involved in endoplasmic reticulum to Golgi vesicle-mediated transport and positive regulation of synapse pruning. Located in cis-Golgi network and endoplasmic reticulum exit site. Is expressed in adult head. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Yif1 in Genome Data Viewer
    Location:
    97C5-97C5; 3-91 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (26717871..26719806)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (22543593..22545528)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene amontillado Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. amontillado, the Drosophila homolog of the prohormone processing protease PC2, is required during embryogenesis and early larval development. Rayburn LY, et al. Genetics, 2003 Jan. PMID 12586710, Free PMC Article
    2. A docked mutation phenocopies dumpy oblique alleles via altered vesicle trafficking. Kandasamy S, et al. PeerJ, 2021. PMID 34721959, Free PMC Article
    3. Yif1 associates with Yip1 on Golgi and regulates dendrite pruning in sensory neurons during Drosophila metamorphosis. Wang Q, et al. Development, 2018 Jun 13. PMID 29769219
    4. Pleiotropic fitness effects of the Tre1-Gr5a region in Drosophila melanogaster. Rollmann SM, et al. Nat Genet, 2006 Jul. PMID 16783380
    5. A whole genome RNAi screen of Drosophila S2 cell spreading performed using automated computational image analysis. D'Ambrosio MV, et al. J Cell Biol, 2010 Nov 1. PMID 21041442, Free PMC Article

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of synapse pruning IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in COPII-coated ER to Golgi transport vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in Golgi membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cis-Golgi network IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in endoplasmic reticulum exit site IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in endoplasmic reticulum-Golgi intermediate compartment IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Yip1-interacting factor 1
    Names
    CG5484-PA
    CG5484-PB
    CG5484-PC
    Yif1-PA
    Yif1-PB
    Yif1-PC
    Yip1d-interacting factor 1
    docked

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      26717871..26719806
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_143241.2 → NP_651498.1  Yip1-interacting factor 1, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651498.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A891LYC2, Q8IMR4
      Related
      FBpp0084411
      Conserved Domains (1) summary
      pfam03878
      Location:142 → 383
      YIF1; YIF1

    2. NM_170284.2 → NP_733163.1  Yip1-interacting factor 1, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_733163.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MTA2, Q9VBC5
      Related
      FBpp0084409
      Conserved Domains (1) summary
      pfam03878
      Location:137 → 378
      YIF1; YIF1

    3. NM_170285.2 → NP_733164.1  Yip1-interacting factor 1, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_733164.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IMR3, Q8MTA2
      Related
      FBpp0084410
      Conserved Domains (1) summary
      pfam03878
      Location:133 → 374
      YIF1; YIF1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IGH0 Q8IGH0
    Q8IMR3 Q8IMR3
    Q8IMR4 Q8IMR4
    Q8MTA2 Q8MTA2
    Q9VBC5 Q9VBC5

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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