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    mrt martik [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43291, updated on 9-Dec-2024

    Summary

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    Official Symbol
    mrtprovided by FlyBase
    Official Full Name
    martikprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039507
    Locus tag
    Dmel_CG3361
    See related
    AllianceGenome:FB:FBgn0039507
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG3361; Dmel\CG3361
    Summary
    Enables transcription cis-regulatory region binding activity. Involved in negative regulation of DNA-templated transcription and regulation of chromatin organization. Located in nucleus. Is expressed in several structures, including gland; larval central nervous system; larval insulin secreting cell of pars intercerebralis; larval ventral nerve cord; and spermatozoon. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See mrt in Genome Data Viewer
    Location:
    97F1-97F1; 3-93 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (27277249..27282661, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (23102971..23108383, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene lethal (3) malignant brain tumor Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene bigmax Neighboring gene Hemomucin Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Preferential ethanol consumption in Drosophila models features of addiction. Devineni AV, et al. Curr Biol, 2009 Dec 29. PMID 20005106, Free PMC Article
    2. BAP60 plays an opposite role to the MRT-NURF complex in regulating lipid droplet size. Yao Y, et al. J Genet Genomics, 2022 Apr. PMID 35196573
    3. Downregulation of Perilipin1 by the Immune Deficiency Pathway Leads to Lipid Droplet Reconfiguration and Adaptation to Bacterial Infection in Drosophila. Wang L, et al. J Immunol, 2021 Nov 1. PMID 34588219
    4. MRT, Functioning with NURF Complex, Regulates Lipid Droplet Size. Yao Y, et al. Cell Rep, 2018 Sep 11. PMID 30208321
    5. Amplification of the 1731 LTR retrotransposon in Drosophila melanogaster cultured cells: origin of neocopies and impact on the genome. Maisonhaute C, et al. Gene, 2007 May 15. PMID 17382490

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables transcription cis-regulatory region binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of DNA-templated transcription IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of chromatin organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    martik
    Names
    CG3361-PA
    CG3361-PB
    CG3361-PC
    CG3361-PD
    CG3361-PE
    CG3361-PF
    mrt-PA
    mrt-PB
    mrt-PC
    mrt-PD
    mrt-PE
    mrt-PF

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      27277249..27282661 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001260398.1 → NP_001247327.1  martik, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001247327.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q494L8, Q9VB49
      Conserved Domains (1) summary
      pfam13837
      Location:120 → 201
      Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain

    2. NM_143297.3 → NP_651554.1  martik, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651554.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q494L8, Q9VB49
      Related
      FBpp0084544
      Conserved Domains (1) summary
      pfam13837
      Location:120 → 201
      Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain

    3. NM_001260399.1 → NP_001247328.1  martik, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001247328.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q494L8, Q9VB49
      Conserved Domains (1) summary
      pfam13837
      Location:120 → 201
      Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain

    4. NM_001260402.1 → NP_001247331.1  martik, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001247331.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q494L8, Q9VB49
      Conserved Domains (1) summary
      pfam13837
      Location:120 → 201
      Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain

    5. NM_001260400.1 → NP_001247329.1  martik, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001247329.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q494L8, Q9VB49
      Conserved Domains (1) summary
      pfam13837
      Location:120 → 201
      Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain

    6. NM_001260401.1 → NP_001247330.1  martik, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001247330.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q494L8, Q9VB49
      Conserved Domains (1) summary
      pfam13837
      Location:120 → 201
      Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VB49 Q9VB49

    Gene LinkOut

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