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    Obp99c Odorant-binding protein 99c [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43494, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Obp99cprovided by FlyBase
    Official Full Name
    Odorant-binding protein 99cprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039682
    Locus tag
    Dmel_CG7584
    See related
    AllianceGenome:FB:FBgn0039682
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    99c; CG7584; DmelObp99c; Dmel\CG7584; Obp 99c; Obp99b
    Summary
    Predicted to enable odorant binding activity. Involved in response to fungus. Predicted to be located in extracellular region. Is expressed in adult head; adult heart; amnioserosa; embryonic/larval fat body; and yolk nucleus. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Obp99c in Genome Data Viewer
    Location:
    99B7-99B7; 3-99 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (29685736..29689311, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (25511458..25515033, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene pickpocket 19 Neighboring gene Bub3 Neighboring gene CAP-D2 condensin subunit Neighboring gene Guanylyl cyclase alpha-subunit at 99B Neighboring gene uncharacterized protein Neighboring gene doublesex-Mab related 99B Neighboring gene long non-coding RNA:CR45569

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Natural variation in odorant recognition among odorant-binding proteins in Drosophila melanogaster. Wang P, et al. Genetics, 2010 Mar. PMID 20026676, Free PMC Article
    2. Cyclophosphamide in Drosophila promotes genes and transposable elements differential expression and mitochondrial dysfunction. Stoffel TJR, et al. Comp Biochem Physiol C Toxicol Pharmacol, 2020 Apr. PMID 31982542
    3. Association of polymorphisms in odorant-binding protein genes with variation in olfactory response to benzaldehyde in Drosophila. Wang P, et al. Genetics, 2007 Nov. PMID 17720903, Free PMC Article
    4. The early developmental gene Semaphorin 5c contributes to olfactory behavior in adult Drosophila. Rollmann SM, et al. Genetics, 2007 Jun. PMID 17435226, Free PMC Article
    5. TBP, Mot1, and NC2 establish a regulatory circuit that controls DPE-dependent versus TATA-dependent transcription. Hsu JY, et al. Genes Dev, 2008 Sep 1. PMID 18703680, Free PMC Article

    See all (53) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables odorant binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables odorant binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in response to fungus HEP PubMed 
    involved_in sensory perception of chemical stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in sensory perception of smell IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Odorant-binding protein 99c
    Names
    CG7584-PA
    CG7584-PB
    Obp99c-PA
    Obp99c-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      29685736..29689311 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001276148.1 → NP_001263077.1  Odorant-binding protein 99c, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001263077.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KI20
      Conserved Domains (1) summary
      cl11600
      Location:2 → 40
      PBP_GOBP; PBP/GOBP family

    2. NM_143454.3 → NP_651711.1  Odorant-binding protein 99c, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651711.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A9QJK9, Q9VAI9
      Related
      FBpp0084829
      Conserved Domains (1) summary
      pfam01395
      Location:17 → 128
      PBP_GOBP; PBP/GOBP family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4KI20 A0A0B4KI20
    Q9VAI9 Q9VAI9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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