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    CG15539 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43627, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG15539provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039782
    Locus tag
    Dmel_CG15539
    See related
    AllianceGenome:FB:FBgn0039782
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG15539-NE4; Dmel\CG15539
    Summary
    Predicted to enable procollagen-proline 4-dioxygenase activity. Predicted to be active in endoplasmic reticulum. Is expressed in adult head. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG15539 in Genome Data Viewer
    Location:
    99F6-99F6; 3-100 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (30505987..30507977)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (26331709..26333699)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene prolyl-4-hydroxylase-alpha SG1 Neighboring gene mir-4908 stem loop Neighboring gene uncharacterized protein Neighboring gene prolyl-4-hydroxylase-alpha NE2 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Prolyl 4-hydroxylase alpha-related proteins in Drosophila melanogaster: tissue-specific embryonic expression of the 99F8-9 cluster. Abrams EW, et al. Mech Dev, 2002 Mar. PMID 11850189
    2. Fork head and Sage maintain a uniform and patent salivary gland lumen through regulation of two downstream target genes, PH4alphaSG1 and PH4alphaSG2. Abrams EW, et al. Development, 2006 Sep. PMID 16914497
    3. Computational and experimental identification of mirtrons in Drosophila melanogaster and Caenorhabditis elegans. Chung WJ, et al. Genome Res, 2011 Feb. PMID 21177960, Free PMC Article
    4. Research gaps and new insights in the evolution of Drosophila seminal fluid proteins. Hurtado J, et al. Insect Mol Biol, 2022 Apr. PMID 34747062
    5. Cold acclimation wholly reorganizes the Drosophila melanogaster transcriptome and metabolome. MacMillan HA, et al. Sci Rep, 2016 Jun 30. PMID 27357258, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables L-ascorbic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables procollagen-proline 4-dioxygenase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables procollagen-proline 4-dioxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG15539-PA
    CG15539-PB
    CG15539-PC
    NP_001036776.1
    NP_001287615.1
    NP_651804.2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      30505987..30507977
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_143547.3 → NP_651804.2  uncharacterized protein Dmel_CG15539, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651804.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4V443, Q9VA62
      Conserved Domains (2) summary
      smart00702
      Location:206 → 371
      P4Hc; Prolyl 4-hydroxylase alpha subunit homologues
      pfam08336
      Location:1 → 33
      P4Ha_N; Prolyl 4-Hydroxylase alpha-subunit, N-terminal region

    2. NM_001043311.2 → NP_001036776.1  uncharacterized protein Dmel_CG15539, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001036776.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0KHY7
      Conserved Domains (2) summary
      smart00702
      Location:329 → 494
      P4Hc; Prolyl 4-hydroxylase alpha subunit homologues
      pfam08336
      Location:33 → 156
      P4Ha_N; Prolyl 4-Hydroxylase alpha-subunit, N-terminal region

    3. NM_001300686.1 → NP_001287615.1  uncharacterized protein Dmel_CG15539, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287615.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4LHW6
      Conserved Domains (2) summary
      smart00702
      Location:328 → 493
      P4Hc; Prolyl 4-hydroxylase alpha subunit homologues
      pfam08336
      Location:33 → 156
      P4Ha_N; Prolyl 4-Hydroxylase alpha-subunit, N-terminal region
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4LHW6 A0A0B4LHW6
    Q0KHY7 Q0KHY7
    Q4V443 Q4V443

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