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    nyo nyobe [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43716, updated on 9-Dec-2024

    Summary

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    Official Symbol
    nyoprovided by FlyBase
    Official Full Name
    nyobeprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039852
    Locus tag
    Dmel_CG1499
    See related
    AllianceGenome:FB:FBgn0039852
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-EST:Liang-2.47; CG1499; clone 2.47; Dmel\CG1499
    Summary
    Involved in apical constriction and regulation of embryonic cell shape. Predicted to be located in membrane. Is expressed in several structures, including embryonic epipharynx; embryonic head epidermis; embryonic head sensory system; embryonic ventral epidermis; and gut section. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See nyo in Genome Data Viewer
    Location:
    100C4-100C6; 3-102 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (31543032..31566165)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (27368754..27391887)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene morpheyus Neighboring gene long non-coding RNA:CR45573 Neighboring gene long non-coding RNA:CR46120 Neighboring gene long non-coding RNA:CR46119

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. gammaCOP is required for apical protein secretion and epithelial morphogenesis in Drosophila melanogaster. Grieder NC, et al. PLoS One, 2008 Sep 19. PMID 18802472, Free PMC Article
    2. SoxNeuro and Shavenbaby act cooperatively to shape denticles in the embryonic epidermis of Drosophila. Rizzo NP, et al. Development, 2017 Jun 15. PMID 28506986, Free PMC Article
    3. nompA encodes a PNS-specific, ZP domain protein required to connect mechanosensory dendrites to sensory structures. Chung YD, et al. Neuron, 2001 Feb. PMID 11239432
    4. Expression of COPI components during development of Drosophila melanogaster. Grieder NC, et al. Gene Expr Patterns, 2005 Dec. PMID 16169286
    5. A family of genes encoding zona pellucida (ZP) domain proteins is expressed in various epithelial tissues during Drosophila embryogenesis. Jaźwińska A, et al. Gene Expr Patterns, 2004 Jul. PMID 15183308

    See all (36) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in anatomical structure morphogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in apical constriction IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of embryonic cell shape IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    nyobe
    Names
    CG1499-PC
    CG1499-PD
    nyo-PC
    nyo-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      31543032..31566165
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_143614.2 → NP_651871.2  nyobe, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651871.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IGS2, Q9V9X0
      Conserved Domains (3) summary
      smart00241
      Location:382 → 618
      ZP; Zona pellucida (ZP) domain
      cd01099
      Location:208 → 286
      PAN_AP_HGF; Subfamily of PAN/APPLE-like domains; present in N-terminal (N) domains of plasminogen/hepatocyte growth factor proteins, and various proteins found in Bilateria, such as leech anti-platelet proteins. PAN/APPLE domains fulfill diverse biological functions ...
      pfam00024
      Location:295 → 374
      PAN_1; PAN domain

    2. NM_170552.2 → NP_733431.2  nyobe, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_733431.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IGS2, Q9V9X0
      Conserved Domains (3) summary
      smart00241
      Location:382 → 618
      ZP; Zona pellucida (ZP) domain
      cd01099
      Location:208 → 286
      PAN_AP_HGF; Subfamily of PAN/APPLE-like domains; present in N-terminal (N) domains of plasminogen/hepatocyte growth factor proteins, and various proteins found in Bilateria, such as leech anti-platelet proteins. PAN/APPLE domains fulfill diverse biological functions ...
      pfam00024
      Location:295 → 374
      PAN_1; PAN domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IGS2 Q8IGS2
    Q9V9X0 Q9V9X0

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