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    CG1638 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43721, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG1638provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039855
    Locus tag
    Dmel_CG1638
    See related
    AllianceGenome:FB:FBgn0039855
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    bs31f06.y1; Dmel\CG1638
    Summary
    Predicted to enable fatty acyl-CoA hydrolase activity. Predicted to be involved in acyl-CoA metabolic process. Predicted to be active in mitochondrion. Is expressed in spermatozoon. Orthologous to human ACOT9 (acyl-CoA thioesterase 9). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG1638 in Genome Data Viewer
    Location:
    100C7-100C7; 3-102 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (31590581..31592316)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (27416303..27418038)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene rough deal Neighboring gene antisense RNA:CR45190 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Ribosomal protein L6

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Lpt, trr, and Hcf regulate histone mono- and dimethylation that are essential for Drosophila heart development. Huang W, et al. Dev Biol, 2022 Oct. PMID 35853502, Free PMC Article
    2. Gene discovery using computational and microarray analysis of transcription in the Drosophila melanogaster testis. Andrews J, et al. Genome Res, 2000 Dec. PMID 11116097, Free PMC Article
    3. Flexible origin of hydrocarbon/pheromone precursors in Drosophila melanogaster. Wicker-Thomas C, et al. J Lipid Res, 2015 Nov. PMID 26353752, Free PMC Article
    4. mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster. Lepennetier G, et al. G3 (Bethesda), 2016 Jun 1. PMID 27172210, Free PMC Article
    5. A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. Neely GG, et al. Cell, 2010 Apr 2. PMID 20371351, Free PMC Article

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables acetyl-CoA hydrolase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables fatty acyl-CoA hydrolase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in acyl-CoA metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in acyl-CoA metabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrial matrix ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG1638-PB
    NP_001097991.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      31590581..31592316
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001104521.2 → NP_001097991.1  uncharacterized protein Dmel_CG1638 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097991.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4V4C3, Q9V9W5
      Conserved Domains (1) summary
      cd03442
      Location:302 → 416
      BFIT_BACH; Brown fat-inducible thioesterase (BFIT). Brain acyl-CoA hydrolase (BACH). These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis, ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9V9W5 Q9V9W5

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