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    CARPB Carbonic anhydrase-related protein B [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31915, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CARPBprovided by FlyBase
    Official Full Name
    Carbonic anhydrase-related protein Bprovided by FlyBase
    Primary source
    FLYBASE:FBgn0052698
    Locus tag
    Dmel_CG32698
    See related
    AllianceGenome:FB:FBgn0052698
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG32698; CG9678; CG9683; Dmel\CG32698
    Summary
    Predicted to enable hydro-lyase activity. Predicted to be involved in one-carbon metabolic process. Orthologous to human CA10 (carbonic anhydrase 10) and CA11 (carbonic anhydrase 11). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CARPB in Genome Data Viewer
    Location:
    9A1-9A2; 1-30 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (9783223..9855449)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (9677256..9749482)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Sp1 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Ser7

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Carbonic anhydrases and anion transport in mosquito midgut pH regulation. Linser PJ, et al. J Exp Biol, 2009 Jun. PMID 19448076, Free PMC Article
    2. Non-redundant selector and growth-promoting functions of two sister genes, buttonhead and Sp1, in Drosophila leg development. Estella C, et al. PLoS Genet, 2010 Jun 24. PMID 20585625, Free PMC Article
    3. A global timing mechanism regulates cell-type-specific wiring programmes. Jain S, et al. Nature, 2022 Mar. PMID 35197627
    4. An expanded toolkit for gene tagging based on MiMIC and scarless CRISPR tagging in Drosophila. Li-Kroeger D, et al. Elife, 2018 Aug 9. PMID 30091705, Free PMC Article
    5. Genetic architecture of natural variation in visual senescence in Drosophila. Carbone MA, et al. Proc Natl Acad Sci U S A, 2016 Oct 25. PMID 27791033, Free PMC Article

    See all (34) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables carbonate dehydratase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydro-lyase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    carbonic anhydrase-related protein B
    Names
    CARPB-PA
    CARPB-PB
    CARPB-PC
    CARPB-PD
    CG32698-PA
    CG32698-PB
    CG32698-PC
    CG32698-PD
    NP_001245593.1
    NP_001259390.1
    NP_001285061.1
    NP_572581.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      9783223..9855449
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298132.1 → NP_001285061.1  carbonic anhydrase-related protein B, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285061.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q961F5, Q9W316
      Conserved Domains (1) summary
      cd03121
      Location:37 → 298
      alpha_CARP_X_XI_like; Carbonic anhydrase alpha related protein: groups X, XI and related proteins. This subgroup contains carbonic anhydrase related proteins (CARPs) X and XI, which have been implicated in various biological processes of the central nervous system. CARPs are ...

    2. NM_001258664.2 → NP_001245593.1  carbonic anhydrase-related protein B, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001245593.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q961F5, Q9W316
      Conserved Domains (1) summary
      cd03121
      Location:37 → 298
      alpha_CARP_X_XI_like; Carbonic anhydrase alpha related protein: groups X, XI and related proteins. This subgroup contains carbonic anhydrase related proteins (CARPs) X and XI, which have been implicated in various biological processes of the central nervous system. CARPs are ...

    3. NM_132353.3 → NP_572581.1  carbonic anhydrase-related protein B, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572581.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q961F5, Q9W316
      Related
      FBpp0071321
      Conserved Domains (1) summary
      cd03121
      Location:37 → 298
      alpha_CARP_X_XI_like; Carbonic anhydrase alpha related protein: groups X, XI and related proteins. This subgroup contains carbonic anhydrase related proteins (CARPs) X and XI, which have been implicated in various biological processes of the central nervous system. CARPs are ...

    4. NM_001272461.1 → NP_001259390.1  carbonic anhydrase-related protein B, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259390.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q961F5, Q9W316
      Conserved Domains (1) summary
      cd03121
      Location:37 → 298
      alpha_CARP_X_XI_like; Carbonic anhydrase alpha related protein: groups X, XI and related proteins. This subgroup contains carbonic anhydrase related proteins (CARPs) X and XI, which have been implicated in various biological processes of the central nervous system. CARPs are ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W316 Q9W316

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