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    CG9270 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35366, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG9270provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0032908
    Locus tag
    Dmel_CG9270
    See related
    AllianceGenome:FB:FBgn0032908
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    DmCG9270; Dmel\CG9270; Dme_CG9270
    Summary
    Predicted to enable ATPase-coupled transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be active in membrane. Is expressed in adult head. Orthologous to human ABCC4 (ATP binding cassette subfamily C member 4 (PEL blood group)). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG9270 in Genome Data Viewer
    Location:
    38F6-38F6; 2-54 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (20929456..20934113, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (20929456..20934113, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene Nth-like DNA glycosylase 1 Neighboring gene Replication protein A2 Neighboring gene long non-coding RNA:CR44606 Neighboring gene uncharacterized protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The dMRP/CG6214 gene of Drosophila is evolutionarily and functionally related to the human multidrug resistance-associated protein family. Tarnay JN, et al. Insect Mol Biol, 2004 Oct. PMID 15373810
    2. Identification and characterization of a heme exporter from the MRP family in Drosophila melanogaster. Wang Z, et al. BMC Biol, 2022 Jun 2. PMID 35655259, Free PMC Article
    3. Characterization of a novel pesticide transporter and P-glycoprotein orthologues in Drosophila melanogaster. Denecke S, et al. Proc Biol Sci, 2022 May 25. PMID 35582794, Free PMC Article
    4. Infection Dynamics and Immune Response in a Newly Described Drosophila-Trypanosomatid Association. Hamilton PT, et al. mBio, 2015 Sep 15. PMID 26374124, Free PMC Article
    5. Identification of genetic loci that interact with cut during Drosophila wing-margin development. Krupp JJ, et al. Genetics, 2005 Aug. PMID 15956666, Free PMC Article

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ABC-type transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATPase-coupled transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG9270-PC
    NP_995741.2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      20929456..20934113 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_206019.2 → NP_995741.2  uncharacterized protein Dmel_CG9270 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_995741.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7KT22, Q9VIG9
      Conserved Domains (4) summary
      cd03244
      Location:1029 → 1250
      ABCC_MRP_domain2; ATP-binding cassette domain 2 of multidrug resistance-associated protein
      cd03250
      Location:412 → 611
      ABCC_MRP_domain1; ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C
      TIGR01271
      Location:6 → 1257
      CFTR_protein; cystic fibrosis transmembrane conductor regulator (CFTR)
      cl00549
      Location:92 → 362
      ABC_membrane; ABC transporter transmembrane region
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7KT22 Q7KT22
    Q7YU06 Q7YU06

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