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    CG8460 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34115, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG8460provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031996
    Locus tag
    Dmel_CG8460
    See related
    AllianceGenome:FB:FBgn0031996
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG8460
    Summary
    Predicted to enable oligosaccharide binding activity. Predicted to be involved in carbohydrate metabolic process. Located in endomembrane system. Is expressed in adult head. Orthologous to human CHID1 (chitinase domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG8460 in Genome Data Viewer
    Location:
    28F1-28F1; 2-30 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (8197193..8198813)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (8197193..8198813)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR44116 Neighboring gene Post-GPI attachment to proteins 5 Neighboring gene antisense RNA:CR44119 Neighboring gene Sodium/solute co-transporter-like 5A11

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Chitinase family GH18: evolutionary insights from the genomic history of a diverse protein family. Funkhouser JD, et al. BMC Evol Biol, 2007 Jun 26. PMID 17594485, Free PMC Article
    2. Tramtrack is genetically upstream of genes controlling tracheal tube size in Drosophila. Rotstein B, et al. PLoS One, 2011. PMID 22216153, Free PMC Article
    3. The biology of insect chitinases and their roles at chitinous cuticles. Rabadiya D, et al. Insect Biochem Mol Biol, 2024 Feb. PMID 38184175
    4. Manual curation and phylogenetic analysis of chitinase family genes in the Asian citrus psyllid, Diaphorina citri. Shippy TD, et al. GigaByte, 2022. PMID 36824529, Free PMC Article
    5. Cell-Surface Proteomic Profiling in the Fly Brain Uncovers Wiring Regulators. Li J, et al. Cell, 2020 Jan 23. PMID 31955847, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables chitin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oligosaccharide binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in endomembrane system HDA PubMed 
    is_active_in endomembrane system IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in extracellular space ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG8460-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      8197193..8198813
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135346.4 → NP_609190.2  uncharacterized protein Dmel_CG8460 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609190.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95RR3, Q9VLS0
      Related
      FBpp0079207
      Conserved Domains (2) summary
      cd02876
      Location:81 → 402
      GH18_SI-CLP; Stabilin-1 interacting chitinase-like protein (SI-CLP) is a eukaryotic chitinase-like protein of unknown function that interacts with the endocytic/sorting transmembrane receptor stabilin-1 and is secreted from the lysosome. SI-CLP has a glycosyl ...
      smart00636
      Location:86 → 393
      Glyco_18; Glyco_18 domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VLS0 Q9VLS0

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