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    AIM3 Aim3p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852405, updated on 9-Dec-2024

    Summary

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    Official Symbol
    AIM3
    Official Full Name
    Aim3p
    Primary source
    SGD:S000000312
    Locus tag
    YBR108W
    See related
    AllianceGenome:SGD:S000000312; FungiDB:YBR108W; VEuPathDB:YBR108W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in actin cortical patch assembly and barbed-end actin filament capping. Located in actin cortical patch and membrane raft. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See AIM3 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_001134.8 (454822..457665)

    Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene Snd3p Neighboring gene Iml3p Neighboring gene calmodulin Neighboring gene chitobiosyldiphosphodolichol beta-1,4 mannosyltransferase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001134.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. SCRaMbLE: A Study of Its Robustness and Challenges through Enhancement of Hygromycin B Resistance in a Semi-Synthetic Yeast. Ong JY, et al. Bioengineering (Basel), 2021 Mar 23. PMID 33806931, Free PMC Article
    2. Actin filament elongation in Arp2/3-derived networks is controlled by three distinct mechanisms. Michelot A, et al. Dev Cell, 2013 Jan 28. PMID 23333351, Free PMC Article
    3. Characterizing the sphingolipid signaling pathway that remediates defects associated with loss of the yeast amphiphysin-like orthologs, Rvs161p and Rvs167p. Germann M, et al. J Biol Chem, 2005 Feb 11. PMID 15561700
    4. Protein interaction networks by proteome peptide scanning. Landgraf C, et al. PLoS Biol, 2004 Jan. PMID 14737190, Free PMC Article
    5. An actin depolymerizing agent 19,20-epoxycytochalasin Q of Xylaria sp. BCC 1067 enhanced antifungal action of azole drugs through ROS-mediated cell death in yeast. Somboon P, et al. Microbiol Res, 2021 Feb. PMID 33227681

    See all (41) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in actin cortical patch assembly IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in barbed-end actin filament capping IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in barbed-end actin filament capping IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in actin cortical patch IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in actin cortical patch IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane raft IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane raft IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Aim3p
    NP_009666.3
    • Protein that inhibits barbed-end actin filament elongation; interacts with Rvs167p; null mutant is viable and displays elevated frequency of mitochondrial genome loss

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001134.8 Reference assembly

      Range
      454822..457665
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178456.2 → NP_009666.3  TPA: Aim3p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_009666.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      C7GUK6, D6VQA7, P38266
      UniProtKB/TrEMBL
      N1PAS9
      Conserved Domains (1) summary
      pfam17096
      Location:8 → 99
      AIM3; Altered inheritance of mitochondria protein 3
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P38266.3

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