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    eelo-1 Early ELOngation arrest [ Caenorhabditis elegans ]

    Gene ID: 175309, updated on 9-Dec-2024

    Summary

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    Official Symbol
    eelo-1
    Official Full Name
    Early ELOngation arrest
    Primary source
    WormBase:WBGene00022057
    Locus tag
    CELE_Y67D2.7
    See related
    AllianceGenome:WB:WBGene00022057
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in regulation of DNA-templated transcription. Predicted to be active in nucleus. Orthologous to human SAP30BP (SAP30 binding protein). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See eelo-1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    5
    Sequence:
    Chromosome: III; NC_003281.10 (1555410..1558529, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Iron-binding zinc finger CDGSH type domain-containing protein Neighboring gene putative ATP-dependent RNA helicase DHX35 homolog Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Ubiquitin carboxyl-terminal hydrolase Neighboring gene ncRNA Neighboring gene Rab proteins geranylgeranyltransferase component A 1 Neighboring gene tRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The TORC1 phosphoproteome in C. elegans reveals roles in transcription and autophagy. Sewell AK, et al. iScience, 2022 May 20. PMID 35479415, Free PMC Article
    2. DEPS-1 is required for piRNA-dependent silencing and PIWI condensate organisation in Caenorhabditis elegans. Suen KM, et al. Nat Commun, 2020 Aug 25. PMID 32843637, Free PMC Article
    3. RNA targets and specificity of Staufen, a double-stranded RNA-binding protein in Caenorhabditis elegans. LeGendre JB, et al. J Biol Chem, 2013 Jan 25. PMID 23195953, Free PMC Article
    4. SIN-3 acts in distinct complexes to regulate the germline transcriptional program in Caenorhabditis elegans. Robert VJ, et al. Development, 2023 Nov 1. PMID 37818613, Free PMC Article
    5. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Early ELOngation arrest
    NP_497421.2
    • Confirmed by transcript evidence;
      Product from WormBase gene class eelo

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      1555410..1558529 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_065020.7 → NP_497421.2  Early ELOngation arrest [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_497421.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9BKQ7
      Conserved Domains (1) summary
      pfam07818
      Location:202 → 287
      HCNGP; HCNGP-like protein
    Nucleotide Protein
    Heading Accession and Version

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