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    igcm-3 Ig-like domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 180569, updated on 9-Dec-2024

    Summary

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    Official Symbol
    igcm-3
    Official Full Name
    Ig-like domain-containing protein
    Primary source
    WormBase:WBGene00020160
    Locus tag
    CELE_T02C5.3
    See related
    AllianceGenome:WB:WBGene00020160
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules and homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to be located in membrane. Predicted to be active in adherens junction. Is expressed in arcade cell; hypodermis; pharyngeal muscle cell; spermatheca; and vulva. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See igcm-3 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    12
    Sequence:
    Chromosome: X; NC_003284.9 (2698250..2705859, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene MICOS complex subunit MIC60-1 Neighboring gene ncRNA Neighboring gene Membrane-associated protein Neighboring gene TNFR-Cys domain-containing protein Neighboring gene ncRNA Neighboring gene EF-hand domain-containing protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Amino acid and protein specificity of protein fatty acylation in C. elegans. Zhang B, et al. Proc Natl Acad Sci U S A, 2024 Jan 30. PMID 38252833, Free PMC Article
    2. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in homophilic cell adhesion via plasma membrane adhesion molecules IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in adherens junction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Ig-like domain-containing protein
    NP_001123175.1
    • Confirmed by transcript evidence
    NP_001391189.1
    • Confirmed by transcript evidence
    NP_001391195.1
    • Confirmed by transcript evidence
    NP_001391196.1
    • Confirmed by transcript evidence
    NP_001391197.1
    • Confirmed by transcript evidence
    NP_001391198.1
    • Confirmed by transcript evidence
    NP_001391199.1
    • Partially confirmed by transcript evidence
    NP_001391200.1
    • Partially confirmed by transcript evidence
    NP_508479.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      2698250..2705859 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001404193.1 → NP_001391189.1  Ig-like domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A8S4QC16

    2. NM_001129703.4 → NP_001123175.1  Ig-like domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001123175.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A7LPD6
      Conserved Domains (3) summary
      smart00410
      Location:280 → 365
      IG_like; Immunoglobulin like
      pfam13927
      Location:186 → 232
      Ig_3; Immunoglobulin domain
      cl11960
      Location:286 → 313
      Ig; Immunoglobulin domain

    3. NM_076078.6 → NP_508479.2  Ig-like domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_508479.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q22096
      Conserved Domains (3) summary
      smart00410
      Location:280 → 365
      IG_like; Immunoglobulin like
      pfam13927
      Location:186 → 232
      Ig_3; Immunoglobulin domain
      cl11960
      Location:286 → 313
      Ig; Immunoglobulin domain

    4. NM_001404194.1 → NP_001391196.1  Ig-like domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A8S4QB36

    5. NM_001404195.1 → NP_001391198.1  Ig-like domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A8S4QDC4

    6. NM_001404196.1 → NP_001391200.1  Ig-like domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A8S4QBH2

    7. NM_001404197.1 → NP_001391195.1  Ig-like domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A8S4Q9R2

    8. NM_001404198.1 → NP_001391197.1  Ig-like domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A8S4QFI2

    9. NM_001404199.1 → NP_001391199.1  Ig-like domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A8S4QC26
    Nucleotide Protein
    Heading Accession and Version

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