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    flp-16 GQTFVRF-amide [ Caenorhabditis elegans ]

    Gene ID: 174967, updated on 9-Dec-2024

    Summary

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    Official Symbol
    flp-16
    Official Full Name
    GQTFVRF-amide
    Primary source
    WormBase:WBGene00001459
    Locus tag
    CELE_F15D4.8
    See related
    AllianceGenome:WB:WBGene00001459
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in cellular response to carbon dioxide; negative regulation of nematode pharyngeal pumping; and negative regulation of striated muscle contraction. Predicted to be located in extracellular region. Is expressed in nerve ring. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See flp-16 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    2
    Sequence:
    Chromosome: II; NC_003280.10 (13235306..13237417)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene BTAF (TBP-associated factor) homolog Neighboring gene Cactin_mid domain-containing protein Neighboring gene Reactive oxygen species modulator 1 Neighboring gene Peptidase C1A papain C-terminal domain-containing protein Neighboring gene ncRNA Neighboring gene CCHC-type domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Regulation of the pharynx of Caenorhabditis elegans by 5-HT, octopamine, and FMRFamide-like neuropeptides. Rogers CM, et al. J Neurobiol, 2001 Nov 15. PMID 11745661
    2. Functional characterization of the putative orphan neuropeptide G-protein coupled receptor C26F1.6 in Caenorhabditis elegans. Mertens I, et al. FEBS Lett, 2004 Aug 27. PMID 15327975
    3. The response to high CO2 levels requires the neuropeptide secretion component HID-1 to promote pumping inhibition. Sharabi K, et al. PLoS Genet, 2014 Aug. PMID 25101962, Free PMC Article
    4. The ovijector of Ascaris suum: multiple response types revealed by Caenorhabditis elegans FMRFamide-related peptides. Moffett CL, et al. Int J Parasitol, 2003 Jul 30. PMID 12865086
    5. Role of a FMRFamide-like family of neuropeptides in the pharyngeal nervous system of Caenorhabditis elegans. Papaioannou S, et al. J Neurobiol, 2005 Dec. PMID 16187307

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in cellular response to carbon dioxide IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of nematode pharyngeal pumping IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of striated muscle contraction IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in neuropeptide signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in neuropeptide signaling pathway TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in extracellular region TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    GQTFVRF-amide
    NP_001379402.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      13235306..13237417
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001393218.1 → NP_001379402.1  GQTFVRF-amide [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q7YX32
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7YX32.1

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