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    • Showing Current items.

    golg-5 Golgin-84 [ Caenorhabditis elegans ]

    Gene ID: 172527, updated on 9-Dec-2024

    Summary

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    Official Symbol
    golg-5
    Official Full Name
    Golgin-84
    Primary source
    WormBase:WBGene00011975
    Locus tag
    CELE_T24B1.1
    See related
    AllianceGenome:WB:WBGene00011975
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable protein homodimerization activity. Predicted to be involved in Golgi organization and retrograde transport, vesicle recycling within Golgi. Predicted to be located in Golgi apparatus. Predicted to be active in Golgi cisterna and Golgi membrane. Orthologous to human GOLGA5 (golgin A5). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See golg-5 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    8
    Sequence:
    Chromosome: I; NC_003279.8 (7676668..7679046)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene DEgenerin Like Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene HAUS6_N domain-containing protein;Vacuolar protein sorting-associated protein VTA1 homolog Neighboring gene Rho-GAP domain-containing protein Neighboring gene eLRR (extracellular Leucine-Rich Repeat) ONly

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The golgin coiled-coil proteins of the Golgi apparatus. Munro S. Cold Spring Harb Perspect Biol, 2011 Jun 1. PMID 21436057, Free PMC Article
    2. Defect-buffering cellular plasticity increases robustness of metazoan embryogenesis. Xiao L, et al. Cell Syst, 2022 Aug 17. PMID 35882226
    3. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables protein homodimerization activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in Golgi organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in Golgi organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in Golgi organization ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in Golgi vesicle transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in retrograde transport, vesicle recycling within Golgi IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in Golgi apparatus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in Golgi cisterna IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in Golgi membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Golgin-84
    NP_492137.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      7676668..7679046
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_059736.6 → NP_492137.1  Golgin-84 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_492137.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P90970, P91831
      Conserved Domains (3) summary
      pfam09787
      Location:89 → 538
      Golgin_A5; Golgin subfamily A member 5
      cd16269
      Location:398 → 409
      GBP_C; coiled coil [structural motif]
      cl20817
      Location:267 → 424
      GBP_C; Guanylate-binding protein, C-terminal domain
    Nucleotide Protein
    Heading Accession and Version

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