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    cec-8 Chromo domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 175202, updated on 9-Dec-2024

    Summary

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    Official Symbol
    cec-8
    Official Full Name
    Chromo domain-containing protein
    Primary source
    WormBase:WBGene00021913
    Locus tag
    CELE_Y55B1BR.3
    See related
    AllianceGenome:WB:WBGene00021913
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable methylated histone binding activity. Predicted to be involved in chromosome attachment to the nuclear envelope and regulation of gene expression. Predicted to be active in nuclear inner membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See cec-8 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    5
    Sequence:
    Chromosome: III; NC_003281.10 (429338..431749)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Secreted protein Neighboring gene Glyceraldehyde-3-phosphate dehydrogenase Neighboring gene Stromal interaction molecule 1 Neighboring gene AF4/FMR2 C-terminal homology domain-containing protein Neighboring gene AFF-Like homolog

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A small RNA system ensures accurate homologous pairing and unpaired silencing of meiotic chromosomes. Tabara H, et al. EMBO J, 2023 Jun 1. PMID 37078421, Free PMC Article
    2. Predictive models of molecular machines involved in Caenorhabditis elegans early embryogenesis. Gunsalus KC, et al. Nature, 2005 Aug 11. PMID 16094371
    3. A transcriptional cofactor regulatory network for the C. elegans intestine. Horowitz BB, et al. G3 (Bethesda), 2023 Jul 5. PMID 37119809, Free PMC Article
    4. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables methylated histone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables methylated histone binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in chromosome attachment to the nuclear envelope IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in chromosome attachment to the nuclear envelope IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of gene expression IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nuclear inner membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Chromo domain-containing protein
    NP_497198.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      429338..431749
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_064797.6 → NP_497198.1  Chromo domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_497198.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95XW8
      Conserved Domains (1) summary
      cd18961
      Location:114 → 167
      CD_CEC-4_like; chromodomain of Caenorhabditis elegans chromodomain protein 4, and similar proteins
    Nucleotide Protein
    Heading Accession and Version

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