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    lips-10 LIPaSe related [ Caenorhabditis elegans ]

    Gene ID: 174345, updated on 9-Dec-2024

    Summary

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    Official Symbol
    lips-10
    Official Full Name
    LIPaSe related
    Primary source
    WormBase:WBGene00008803
    Locus tag
    CELE_F14E5.5
    See related
    AllianceGenome:WB:WBGene00008803
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable lipase activity. Predicted to be involved in lipid catabolic process. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See lips-10 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    4
    Sequence:
    Chromosome: II; NC_003280.10 (8439168..8442151)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene ACid Phosphatase family Neighboring gene ACid Phosphatase family Neighboring gene Eukaryotic translation initiation factor 3 subunit G Neighboring gene ADP-ribosylation factor-like protein 2 Neighboring gene Cuticlin-3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Hypoxic response regulators RHY-1 and EGL-9/PHD promote longevity through a VHL-1-independent transcriptional response. Kruempel JCP, et al. Geroscience, 2020 Dec. PMID 32399915, Free PMC Article
    2. Reduced insulin/IGF1 signaling prevents immune aging via ZIP-10/bZIP-mediated feedforward loop. Lee Y, et al. J Cell Biol, 2021 May 3. PMID 33666644, Free PMC Article
    3. Comparative genomics and functional study of lipid metabolic genes in Caenorhabditis elegans. Zhang Y, et al. BMC Genomics, 2013 Mar 12. PMID 23496871, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables lipase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in lipid catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in lipid catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    LIPaSe related
    NP_495777.1
    • Product from WormBase gene class lips;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      8439168..8442151
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_063376.9 → NP_495777.1  LIPaSe related [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495777.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q19462
      Conserved Domains (1) summary
      pfam01674
      Location:64 → 276
      Lipase_2; Lipase (class 2)
    Nucleotide Protein
    Heading Accession and Version

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