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    fpn-1.2 Solute carrier family 40 member [ Caenorhabditis elegans ]

    Gene ID: 187727, updated on 9-Dec-2024

    Summary

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    Official Symbol
    fpn-1.2
    Official Full Name
    Solute carrier family 40 member
    Primary source
    WormBase:WBGene00019977
    Locus tag
    CELE_R09B5.4
    See related
    AllianceGenome:WB:WBGene00019977
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable iron ion transmembrane transporter activity. Predicted to be involved in iron ion transmembrane transport. Predicted to be located in membrane. Is expressed in pharynx. Human ortholog(s) of this gene implicated in hemochromatosis type 4. Orthologous to human SLC40A1 (solute carrier family 40 member 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See fpn-1.2 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    6
    Sequence:
    Chromosome: V; NC_003283.11 (1462011..1464699, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Glyco_18 domain-containing protein Neighboring gene 3-hydroxyacyl-CoA dehydrogenase Neighboring gene Prion-like-(Q/N-rich)-domain-bearing protein Neighboring gene CTLH domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    2. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables iron ion transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in iron ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in monoatomic ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Solute carrier family 40 member
    NP_503422.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      1462011..1464699 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_071021.3 → NP_503422.2  Solute carrier family 40 member [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      O44607
      Conserved Domains (1) summary
      pfam06963
      Location:16 → 465
      FPN1; Ferroportin1 (FPN1)
    Nucleotide Protein
    Heading Accession and Version

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