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    abu-2 Activated in Blocked Unfolded protein response [ Caenorhabditis elegans ]

    Gene ID: 184695, updated on 27-Dec-2024

    Summary

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    Official Symbol
    abu-2
    Official Full Name
    Activated in Blocked Unfolded protein response
    Primary source
    WormBase:WBGene00000025
    Locus tag
    CELE_F19G12.7
    See related
    AllianceGenome:WB:WBGene00000025
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in endoplasmic reticulum unfolded protein response. Predicted to be active in endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See abu-2 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    2
    Sequence:
    Chromosome: X; NC_003284.9 (1408836..1410652, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Protein FAR1-RELATED SEQUENCE Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Serpentine Receptor, class H Neighboring gene Uncharacterized protein Neighboring gene Uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A role for SIR-2.1 regulation of ER stress response genes in determining C. elegans life span. Viswanathan M, et al. Dev Cell, 2005 Nov. PMID 16256736
    2. A survival pathway for Caenorhabditis elegans with a blocked unfolded protein response. Urano F, et al. J Cell Biol, 2002 Aug 19. PMID 12186849, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in endoplasmic reticulum unfolded protein response HEP PubMed 
    involved_in endoplasmic reticulum unfolded protein response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Activated in Blocked Unfolded protein response
    NP_508265.1
    • Product from WormBase gene class abu;
      Predicted

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      1408836..1410652 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_075864.1 → NP_508265.1  Activated in Blocked Unfolded protein response [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_508265.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q19594
      Conserved Domains (1) summary
      pfam06493
      Location:20 → 69
      DUF1096; Protein of unknown function (DUF1096)
    Nucleotide Protein
    Heading Accession and Version

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