nhr-188 Nuclear Hormone Receptor family [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: nhr-188
Official Full Name: Nuclear Hormone Receptor family
Primary source: WormBase:WBGene00018544
Locus tag: CELE_F47C10.7
See related: AllianceGenome:WB:WBGene00018544
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Is expressed in head neurons and tail neurons. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See nhr-188 in Genome Data Viewer

Location:: chromosome: V

Exon count:: 6

Sequence:: Chromosome: V; NC_003283.11 (3856296..3857861, complement)

Chromosome V - NC_003283.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

F47C10.7 (e-PCR)
- UniSTS:306323

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription factor activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Nuclear Hormone Receptor family

NP_001317819.1

Partially confirmed by transcript evidence

NP_504064.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003283.11 Reference assembly

Range

3856296..3857861 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_071663.2 → NP_504064.1 Nuclear Hormone Receptor family [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_504064.1

Status: REVIEWED

UniProtKB/TrEMBL

O01562

Conserved Domains (2) summary

smart00399
Location:16 → 84

ZnF_C4; c4 zinc finger in nuclear hormone receptors

smart00430
Location:162 → 322

HOLI; Ligand binding domain of hormone receptors
NM_001330816.1 → NP_001317819.1 Nuclear Hormone Receptor family [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

A0A168H5N7