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    H43I07.1 OPA3-like protein;Peroxin-14 [ Caenorhabditis elegans ]

    Gene ID: 178824, updated on 9-Dec-2024

    Summary

    Official Symbol
    H43I07.1
    Official Full Name
    OPA3-like protein;Peroxin-14
    Primary source
    WormBase:WBGene00019274
    Locus tag
    CELE_H43I07.1
    See related
    AllianceGenome:WB:WBGene00019274
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in regulation of lipid metabolic process. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in 3-methylglutaconic aciduria type 3 and optic atrophy 3. Orthologous to human OPA3 (outer mitochondrial membrane lipid metabolism regulator OPA3). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See H43I07.1 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    5
    Sequence:
    Chromosome: V; NC_003283.11 (4204721..4209760)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Dolichyl-phosphate beta-glucosyltransferase;dolichyl-phosphate beta-glucosyltransferase Neighboring gene DNA-directed RNA polymerase RpoA/D/Rpb3-type domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene Neuropeptide-Like Protein

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in regulation of lipid metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    OPA3-like protein;Peroxin-14
    NP_001317827.1
    • Confirmed by transcript evidence
    NP_001380198.1
    • Confirmed by transcript evidence
    NP_504167.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      4204721..4209760
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_071766.4NP_504167.2  Peroxin-14 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A168H995
    2. NM_001330842.4NP_001317827.1  OPA3-like protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A168H9C2
    3. NM_001392499.1NP_001380198.1  OPA3-like protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A163VU72
      Conserved Domains (2) summary
      pfam07047
      Location:3136
      OPA3; Optic atrophy 3 protein (OPA3)
      cl26593
      Location:122176
      DUF2076; Uncharacterized protein conserved in bacteria (DUF2076)