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    C35D10.10 Thioredoxin-related transmembrane protein 2 homolog [ Caenorhabditis elegans ]

    Gene ID: 175646, updated on 9-Dec-2024

    Summary

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    Official Symbol
    C35D10.10
    Official Full Name
    Thioredoxin-related transmembrane protein 2 homolog
    Primary source
    WormBase:WBGene00016446
    Locus tag
    CELE_C35D10.10
    See related
    AllianceGenome:WB:WBGene00016446
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable disulfide oxidoreductase activity. Predicted to be located in membrane. Orthologous to human TMX2 (thioredoxin related transmembrane protein 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See C35D10.10 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    4
    Sequence:
    Chromosome: III; NC_003281.10 (4860683..4861794, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene PH domain-containing protein Neighboring gene ULP_PROTEASE domain-containing protein Neighboring gene NADP-dependent oxidoreductase domain-containing protein Neighboring gene Ubiquinol-cytochrome c chaperone domain-containing protein Neighboring gene Atypical kinase coq-8, mitochondrial

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A global analysis of genetic interactions in Caenorhabditis elegans. Byrne AB, et al. J Biol, 2007. PMID 17897480, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables disulfide oxidoreductase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in membrane-bounded organelle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Thioredoxin-related transmembrane protein 2 homolog
    NP_498012.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      4860683..4861794 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_065611.6 → NP_498012.1  Thioredoxin-related transmembrane protein 2 homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_498012.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q18484
      Conserved Domains (1) summary
      cd02962
      Location:98 → 248
      TMX2; TMX2 family; composed of proteins similar to human TMX2, a 372-amino acid TRX-related transmembrane protein, identified and characterized through the cloning of its cDNA from a human fetal library. It contains a TRX domain but the redox active CXXC motif ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q18484.1

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