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    ceh-54 Homeobox domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 188474, updated on 9-Dec-2024

    Summary

    Official Symbol
    ceh-54
    Official Full Name
    Homeobox domain-containing protein
    Primary source
    WormBase:WBGene00020485
    Locus tag
    CELE_T13C5.4
    See related
    AllianceGenome:WB:WBGene00020485
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in neurons. Orthologous to several human genes including ESX1 (ESX homeobox 1); RHOXF1 (Rhox homeobox family member 1); and RHOXF2 (Rhox homeobox family member 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See ceh-54 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    4
    Sequence:
    Chromosome: X; NC_003284.9 (6191605..6194241, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene DUF281 domain-containing protein Neighboring gene Secreted protein Neighboring gene 3-ketosteroid oxygenase;Cytochrome P450 Neighboring gene Beta carbonic anhydrase 1

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Homeobox domain-containing protein
    NP_001338798.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      6191605..6194241 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001351883.3NP_001338798.1  Homeobox domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q22459
      Conserved Domains (1) summary
      pfam00046
      Location:49102
      Homeobox; Homeobox domain