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    • Showing Current items.

    tba-9 Tubulin alpha chain [ Caenorhabditis elegans ]

    Gene ID: 185538, updated on 9-Dec-2024

    Summary

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    Official Symbol
    tba-9
    Official Full Name
    Tubulin alpha chain
    Primary source
    WormBase:WBGene00006535
    Locus tag
    CELE_F40F4.5
    See related
    AllianceGenome:WB:WBGene00006535
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Predicted to be active in cytoplasm and microtubule. Is expressed in RIG; accessory cell; ciliated neurons; ventral cord neurons; and vulval muscle. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See tba-9 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    9
    Sequence:
    Chromosome: X; NC_003284.9 (3252800..3256269)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Prion-like-(Q/N-rich)-domain-bearing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Cytosolic fatty-acid binding proteins domain-containing protein;Fatty acid-binding protein homolog 3 Neighboring gene Fatty acid-binding protein homolog 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Specific alpha- and beta-tubulin isotypes optimize the functions of sensory Cilia in Caenorhabditis elegans. Hurd DD, et al. Genetics, 2010 Jul. PMID 20421600, Free PMC Article
    2. Expression Patterns and Levels of All Tubulin Isotypes Analyzed in GFP Knock-In C. elegans Strains. Nishida K, et al. Cell Struct Funct, 2021 Jun 30. PMID 33967119, Free PMC Article
    3. Adipocytes control food intake and weight regain via Vacuolar-type H(+) ATPase. Zapata RC, et al. Nat Commun, 2022 Aug 30. PMID 36042358, Free PMC Article
    4. Intraflagellar transport/Hedgehog-related signaling components couple sensory cilium morphology and serotonin biosynthesis in Caenorhabditis elegans. Moussaif M, et al. J Neurosci, 2009 Apr 1. PMID 19339602, Free PMC Article
    5. Microtubule plus-end dynamics link wound repair to the innate immune response. Taffoni C, et al. Elife, 2020 Jan 29. PMID 31995031, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables GTP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in microtubule cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in microtubule-based process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mitotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in microtubule IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Tubulin alpha chain
    NP_508555.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      3252800..3256269
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_076154.6 → NP_508555.2  Tubulin alpha chain [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_508555.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q20221
      Conserved Domains (2) summary
      PTZ00335
      Location:7 → 453
      PTZ00335; tubulin alpha chain; Provisional
      cd02186
      Location:7 → 440
      alpha_tubulin; The alpha-tubulin family
    Nucleotide Protein
    Heading Accession and Version

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