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    C27B7.5 CCHC-type domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 177707, updated on 9-Dec-2024

    Summary

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    Official Symbol
    C27B7.5
    Official Full Name
    CCHC-type domain-containing protein
    Primary source
    WormBase:WBGene00007762
    Locus tag
    CELE_C27B7.5
    See related
    AllianceGenome:WB:WBGene00007762
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable mRNA binding activity; single-stranded RNA binding activity; and translation regulator activity. Predicted to be involved in positive regulation of cytoplasmic translation. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See C27B7.5 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    4
    Sequence:
    Chromosome: IV; NC_003282.8 (8901646..8903177)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Phospholipid scramblase Neighboring gene Helicase ARIP4;Helicase ATP-binding domain-containing protein Neighboring gene Putative serine/threonine-protein phosphatase C27B7.6 Neighboring gene Ig-like and fibronectin type-III domain-containing protein C27B7.7 Neighboring gene ncRNA Neighboring gene INSulin related

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. PETISCO is a novel protein complex required for 21U RNA biogenesis and embryonic viability. Cordeiro Rodrigues RJ, et al. Genes Dev, 2019 Jul 1. PMID 31147388, Free PMC Article
    2. A modified TurboID approach identifies tissue-specific centriolar components in C. elegans. Holzer E, et al. PLoS Genet, 2022 Apr. PMID 35442950, Free PMC Article
    3. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    4. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables enzyme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables single-stranded RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables translation regulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of cytoplasmic translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    CCHC-type domain-containing protein
    NP_501546.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      8901646..8903177
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_069145.7 → NP_501546.1  CCHC-type domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_501546.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q18244
      Conserved Domains (1) summary
      pfam00098
      Location:170 → 185
      zf-CCHC; Zinc knuckle
    Nucleotide Protein
    Heading Accession and Version

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