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    scrt-1 C2H2-type domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 183848, updated on 9-Dec-2024

    Summary

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    Official Symbol
    scrt-1
    Official Full Name
    C2H2-type domain-containing protein
    Primary source
    WormBase:WBGene00016948
    Locus tag
    CELE_C55C2.1
    See related
    AllianceGenome:WB:WBGene00016948
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See scrt-1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    5
    Sequence:
    Chromosome: I; NC_003279.8 (2568860..2571059)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene Sperm-specific class P protein 19 Neighboring gene Amino Acid Transporter Neighboring gene fructose-bisphosphatase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Pairing of competitive and topologically distinct regulatory modules enhances patterned gene expression. Yanai I, et al. Mol Syst Biol, 2008. PMID 18277379, Free PMC Article
    2. FBXO11 promotes ubiquitination of the Snail family of transcription factors in cancer progression and epidermal development. Jin Y, et al. Cancer Lett, 2015 Jun 28. PMID 25827072, Free PMC Article
    3. The C. elegans Snail homolog CES-1 can activate gene expression in vivo and share targets with bHLH transcription factors. Reece-Hoyes JS, et al. Nucleic Acids Res, 2009 Jun. PMID 19372275, Free PMC Article
    4. Transcriptional regulation. Okkema PG, et al. WormBook, 2005 Dec 23. PMID 18050428, Free PMC Article
    5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    C2H2-type domain-containing protein
    NP_491001.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      2568860..2571059
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058600.3 → NP_491001.2  C2H2-type domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491001.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      O01830
      Conserved Domains (3) summary
      sd00017
      Location:96 → 116
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:94 → 116
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:109 → 132
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein
    Heading Accession and Version

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