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    Mrgprf MAS related GPR family member F [ Rattus norvegicus (Norway rat) ]

    Gene ID: 266762, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Mrgprfprovided by RGD
    Official Full Name
    MAS related GPR family member Fprovided by RGD
    Primary source
    RGD:708478
    See related
    EnsemblRapid:ENSRNOG00000013426 AllianceGenome:RGD:708478
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    MrgF
    Summary
    Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in nuclear membrane. Predicted to be active in plasma membrane. Orthologous to human MRGPRF (MAS related GPR family member F). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Uterus (RPKM 57.4), Heart (RPKM 29.3) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Mrgprf in Genome Data Viewer
    Location:
    1q42
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (209893384..209902852)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (200464100..200473588)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (218465642..218476228)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene small integral membrane protein 38 Neighboring gene two pore segment channel 2 Neighboring gene MAS related GPR family member D Neighboring gene immunoglobulin mu DNA binding protein 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. RTA, a candidate G protein-coupled receptor: cloning, sequencing, and tissue distribution. Ross PC, et al. Proc Natl Acad Sci U S A, 1990 Apr. PMID 2109324, Free PMC Article
    2. Atypical expansion in mice of the sensory neuron-specific Mrg G protein-coupled receptor family. Zylka MJ, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12909716, Free PMC Article
    3. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Prunotto M, et al. J Proteomics, 2013 Apr 26. PMID 23376485
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables G protein-coupled receptor activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nuclear membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nuclear membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    mas-related G-protein coupled receptor member F
    Names
    G protein coupled receptor (RTA)
    G protein coupled receptor Rca
    MAS-related G-protein coupled receptor, member F
    MAS-related GPR, member F
    mas-related gene F protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_153722.2 → NP_714944.1  mas-related G-protein coupled receptor member F

      See identical proteins and their annotated locations for NP_714944.1

      Status: PROVISIONAL

      Source sequence(s)
      CR475700, DV716655, M35297
      UniProtKB/Swiss-Prot
      P23749
      UniProtKB/TrEMBL
      A6HYJ6, G3V7Q5
      Related
      ENSRNOP00000017948.7, ENSRNOT00000017948.9
      Conserved Domains (1) summary
      pfam00001
      Location:62 → 291
      7tm_1; 7 transmembrane receptor (rhodopsin family)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      209893384..209902852
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039102519.2 → XP_038958447.1  mas-related G-protein coupled receptor member F isoform X1

      UniProtKB/TrEMBL
      A6HYJ6, G3V7Q5, W8W3G4
      Related
      ENSRNOP00000083488.1, ENSRNOT00000119902.2
      Conserved Domains (2) summary
      cd14964
      Location:30 → 56
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:29 → 302
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P23749.1 GenPept UniProtKB/Swiss-Prot:P23749

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
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