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    Ankdd1a ankyrin repeat and death domain containing 1A [ Rattus norvegicus (Norway rat) ]

    Gene ID: 100362785, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ankdd1aprovided by RGD
    Official Full Name
    ankyrin repeat and death domain containing 1Aprovided by RGD
    Primary source
    RGD:1586052
    See related
    EnsemblRapid:ENSRNOG00000015554 AllianceGenome:RGD:1586052
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in signal transduction. Orthologous to human ANKDD1A (ankyrin repeat and death domain containing 1A). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Lung (RPKM 17.4), Brain (RPKM 9.6) and 7 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Ankdd1a in Genome Data Viewer
    Location:
    8q24
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (74912707..74938870, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (66017571..66043738, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (71034630..71057265, complement)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene mitochondrial methionyl-tRNA formyltransferase Neighboring gene SPG21 abhydrolase domain containing, maspardin Neighboring gene pleckstrin homology domain containing O2 Neighboring gene PIF1 5'-to-3' DNA helicase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ankyrin repeat and death domain-containing protein 1A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      74912707..74938870 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039082474.2 → XP_038938402.1  ankyrin repeat and death domain-containing protein 1A isoform X3

      UniProtKB/TrEMBL
      M0R3S6
      Related
      ENSRNOP00000063997.2, ENSRNOT00000075734.3
      Conserved Domains (3) summary
      PHA03095
      Location:21 → 335
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:181 → 212
      ANK; ANK repeat [structural motif]
      cl14633
      Location:387 → 463
      DD; Death Domain Superfamily of protein-protein interaction domains

    2. XM_017596076.3 → XP_017451565.1  ankyrin repeat and death domain-containing protein 1A isoform X2

      Related
      ENSRNOP00000034966.8, ENSRNOT00000033512.9

    3. XM_006243300.4 → XP_006243362.1  ankyrin repeat and death domain-containing protein 1A isoform X1

      See identical proteins and their annotated locations for XP_006243362.1

      UniProtKB/TrEMBL
      D3Z8Z7
      Conserved Domains (4) summary
      cd00204
      Location:178 → 301
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:153 → 243
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:114 → 169
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:181 → 212
      ANK; ANK repeat [structural motif]

    4. XM_039082475.2 → XP_038938403.1  ankyrin repeat and death domain-containing protein 1A isoform X4

      Conserved Domains (3) summary
      COG0666
      Location:25 → 176
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      sd00045
      Location:73 → 103
      ANK; ANK repeat [structural motif]
      cl14633
      Location:245 → 321
      DD; Death Domain Superfamily of protein-protein interaction domains
    Nucleotide Protein Strain
    Heading Accession and Version

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