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    Lao1 L-amino acid oxidase 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 298483, updated on 9-Dec-2024

    Summary

    Official Symbol
    Lao1provided by RGD
    Official Full Name
    L-amino acid oxidase 1provided by RGD
    Primary source
    RGD:1310787
    See related
    EnsemblRapid:ENSRNOG00000007232 AllianceGenome:RGD:1310787
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable L-amino-acid oxidase activity and polyamine oxidase activity. Predicted to be involved in amino acid catabolic process. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

    See Lao1 in Genome Data Viewer
    Location:
    5q36
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (137859033..137868926)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (132573698..132583591)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (138011760..138021653)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene transfer RNA serine (anticodon AGA) 19 Neighboring gene olfactory receptor family 10 subfamily AK member 7G, pseudogene 1 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene ubiquitin B, pseudogene 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106682.1NP_001100152.1  L-amino acid oxidase 1 precursor

      See identical proteins and their annotated locations for NP_001100152.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474008
      UniProtKB/TrEMBL
      A0A8I5ZZ75, A6JZK6, B5DEI2, F7FCK8
      Related
      ENSRNOP00000009520.5, ENSRNOT00000009520.7
      Conserved Domains (2) summary
      pfam01593
      Location:67504
      Amino_oxidase; Flavin containing amine oxidoreductase
      pfam13450
      Location:62125
      NAD_binding_8; NAD(P)-binding Rossmann-like domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      137859033..137868926
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)