Tmem37 transmembrane protein 37 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Tmem37provided by RGD
Official Full Name: transmembrane protein 37provided by RGD
Primary source: RGD:628689
See related: EnsemblRapid:ENSRNOG00000047714 AllianceGenome:RGD:628689
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Pr; Pr1
Summary: Predicted to enable calcium channel activity and voltage-gated monoatomic ion channel activity. Predicted to be involved in calcium ion transmembrane transport. Predicted to be located in membrane. Predicted to be part of monoatomic ion channel complex. Orthologous to human TMEM37 (transmembrane protein 37). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Kidney (RPKM 207.1), Liver (RPKM 173.3) and 6 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 13q11

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	13	NC_086031.1 (33737096..33743602, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	13	NC_051348.1 (31184322..31191477, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	13	NC_005112.4 (36094665..36101443, complement)

Chromosome 13 - NC_086031.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

AI173373 (e-PCR)
- UniSTS:178453

RH143631 (e-PCR)
- UniSTS:232877

UniSTS:234199 (e-PCR)
- UniSTS:234199

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables calcium channel activity	IEA Inferred from Electronic Annotation more info
enables voltage-gated monoatomic ion channel activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in calcium ion transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
part_of monoatomic ion channel complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: voltage-dependent calcium channel gamma-like subunit

Names: neuronal voltage-gated calcium channel gamma-like subunit; protein distantly related to to the gamma subunit family; voltage-dependent calcium channel gamma subunit-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_139095.2 → NP_620795.2 voltage-dependent calcium channel gamma-like subunit

Status: VALIDATED

Source sequence(s)

JAXUCZ010000013

UniProtKB/TrEMBL

A6K7Y6

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086031.1 Reference GRCr8

Range

33737096..33743602 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_008769424.4 → XP_008767646.1 voltage-dependent calcium channel gamma-like subunit isoform X1

UniProtKB/TrEMBL

A6K7Y6, M0RCX9

Related

ENSRNOP00000067466.2, ENSRNOT00000074471.4

Conserved Domains (1) summary

pfam15108
Location:19 → 199

TMEM37; Voltage-dependent calcium channel gamma-like subunit protein family