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    ATXN8OS ATXN8 opposite strand lncRNA [ Homo sapiens (human) ]

    Gene ID: 6315, updated on 10-Dec-2024

    Summary

    Official Symbol
    ATXN8OSprovided by HGNC
    Official Full Name
    ATXN8 opposite strand lncRNAprovided by HGNC
    Primary source
    HGNC:HGNC:10561
    See related
    Ensembl:ENSG00000230223 MIM:603680; AllianceGenome:HGNC:10561
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    SCA8; KLHL1AS; NCRNA00003
    Summary
    This gene is an antisense transcript to the KLHL1 gene (homolog to the Drosophila KELCH gene); it does not itself appear to be protein coding. A TAC/TGC trinucleotide repeat expansion that is incorporated into this gene transcript, but not the KLHL1 transcript, causes spinocerebellar ataxia type 8. Presumably the expansion interferes with normal antisense function of this transcript. [provided by RefSeq, Oct 2008]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

    See ATXN8OS in Genome Data Viewer
    Location:
    13q21.33
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 13 NC_000013.11 (70107421..70171738)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 13 NC_060937.1 (69329292..69393575)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 13 NC_000013.10 (70681553..70745870)

    Chromosome 13 - NC_000013.11Genomic Context describing neighboring genes Neighboring gene kelch like family member 1 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr13:70544083-70545282 Neighboring gene 5',3'-nucleotidase, cytosolic pseudogene 3 Neighboring gene ATXN8 opposite strand (non-protein coding) repeat instability region Neighboring gene LUC7 like 3 pre-mRNA splicing factor pseudogene 1 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr13:70829090-70829790 Neighboring gene RNA, U6 small nuclear 54, pseudogene Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr13:71204047-71205022 Neighboring gene uncharacterized LOC105370255 Neighboring gene VISTA enhancer hs126 Neighboring gene VISTA enhancer hs540

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    General gene information

    Markers

    Other Names

    • ATXN8 opposite strand (non-protein coding)
    • ataxin 8 opposite strand
    • kelch-like 1 antisense
    • non-protein coding RNA 3

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_016173.1 RefSeqGene

      Range
      5001..37541
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. NR_002717.3 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL160391
    2. NR_185834.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL160391
      Related
      ENST00000678624.1
    3. NR_185835.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL160391
      Related
      ENST00000717782.1
    4. NR_185836.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL160391
    5. NR_185837.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL160391
    6. NR_185838.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL160391
    7. NR_185839.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL160391
      Related
      ENST00000660386.1
    8. NR_185840.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL160391
    9. NR_185841.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL160391
      Related
      ENST00000424524.3
    10. NR_185842.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL160391
      Related
      ENST00000665905.2

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000013.11 Reference GRCh38.p14 Primary Assembly

      Range
      70107421..70171738
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060937.1 Alternate T2T-CHM13v2.0

      Range
      69329292..69393575
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)