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    gammaSnap1 gamma Soluble NSF attachment protein 1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37842, updated on 9-Dec-2024

    Summary

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    Official Symbol
    gammaSnap1provided by FlyBase
    Official Full Name
    gamma Soluble NSF attachment protein 1provided by FlyBase
    Primary source
    FLYBASE:FBgn0028552
    Locus tag
    Dmel_CG3988
    See related
    AllianceGenome:FB:FBgn0028552
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG3988; Dmel\CG3988; gamma SNAP; gamma-Snap; gamma-SNAP; gammaSnap; gammaSNAP-2; gSnap
    Summary
    Predicted to enable soluble NSF attachment protein activity and syntaxin binding activity. Involved in wing disc dorsal/ventral pattern formation. Predicted to be part of SNARE complex. Is expressed in adult head and organism. Orthologous to human NAPG (NSF attachment protein gamma). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See gammaSnap1 in Genome Data Viewer
    Location:
    60B5-60B5; 2-106 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (24047145..24048903, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (19934668..19936426, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene CCR4-NOT transcription complex subunit 11 Neighboring gene Integrator 1 Neighboring gene twinstar Neighboring gene seizure Neighboring gene pickpocket 29 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44814 Neighboring gene eukaryotic translation elongation factor 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Transcription termination between polo and snap, two closely spaced tandem genes of D. melanogaster. Henriques T, et al. Transcription, 2012 Jul-Aug. PMID 22992452, Free PMC Article
    2. Functional and molecular identification of novel members of the ubiquitous membrane fusion proteins alpha- and gamma-SNAP (soluble N-ethylmaleimide-sensitive factor-attachment proteins) families in Dictyostelium discoideum. Weidenhaupt M, et al. Eur J Biochem, 2000 Apr. PMID 10727946
    3. Mechanisms of neurotransmitter release. Littleton JT, et al. Int Rev Neurobiol, 1999. PMID 10218158
    4. Cytokine exocytosis and JAK/STAT activation in the Drosophila ovary requires the vesicle trafficking regulator α-Snap. Saadin A, et al. J Cell Sci, 2018 Nov 30. PMID 30404830, Free PMC Article
    5. Multiple functions of the SNARE protein Snap29 in autophagy, endocytic, and exocytic trafficking during epithelial formation in Drosophila. Morelli E, et al. Autophagy, 2014. PMID 25551675, Free PMC Article

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables soluble NSF attachment protein activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables soluble NSF attachment protein activity NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    enables syntaxin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in intracellular protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in neurotransmitter secretion NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in synaptic vesicle priming NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in wing disc dorsal/ventral pattern formation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of SNARE complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm NAS
    Non-traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    gamma soluble NSF attachment protein 1
    Names
    CG3988-PA
    gamma SNAP
    gamma-soluble NSF attachment protein
    gammaSnap
    gammaSnap1-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      24047145..24048903 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058121.4 → NP_477469.1  gamma soluble NSF attachment protein 1 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_477469.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9U6R9, Q9W1C3
      Related
      FBpp0072096
      Conserved Domains (2) summary
      cd15832
      Location:33 → 70
      SNAP; TPR repeat [structural motif]
      cl24038
      Location:11 → 248
      SNAP; Soluble N-ethylmaleimide-sensitive factor (NSF) Attachment Protein family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9U6R9 Q9U6R9

    Gene LinkOut

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