CG31139 uncharacterized protein [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: CG31139provided by FlyBase
Official Full Name: uncharacterized proteinprovided by FlyBase
Primary source: FLYBASE:FBgn0051139
Locus tag: Dmel_CG31139
See related: AllianceGenome:FB:FBgn0051139
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: BcDNA:AT07872; CG17138; Dmel\CG31139
Summary: Predicted to enable EGF-domain serine glucosyltransferase activity and EGF-domain serine xylosyltransferase activity. Predicted to be involved in positive regulation of Notch signaling pathway and protein O-linked glycosylation. Predicted to be located in endoplasmic reticulum lumen. Predicted to be active in endomembrane system. Human ortholog(s) of this gene implicated in Dowling-Degos disease and autosomal recessive limb-girdle muscular dystrophy type 2Z. Orthologous to human POGLUT1 (protein O-glucosyltransferase 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (22747690..22749056, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (18573412..18574778, complement)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables EGF-domain serine glucosyltransferase activity	ISS Inferred from Sequence or Structural Similarity more info
enables EGF-domain serine xylosyltransferase activity	ISS Inferred from Sequence or Structural Similarity more info
enables UDP-glucosyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables UDP-xylosyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in positive regulation of Notch signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein O-linked glycosylation	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein O-linked glycosylation	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
is_active_in endomembrane system	IBA Inferred from Biological aspect of Ancestor more info
located_in endoplasmic reticulum lumen	ISS Inferred from Sequence or Structural Similarity more info

NP_001262848.1

NP_732797.1

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The following sections contain reference sequences that belong to a specific genome build. Explain