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    Ag5r2 Antigen 5-related 2 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 44079, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ag5r2provided by FlyBase
    Official Full Name
    Antigen 5-related 2provided by FlyBase
    Primary source
    FLYBASE:FBgn0020508
    Locus tag
    Dmel_CG9540
    See related
    AllianceGenome:FB:FBgn0020508
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Agr2; CG9540; Dmel\CG9540
    Summary
    Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in embryonic midgut constriction 3 and embryonic/larval posterior midgut. Orthologous to human R3HDML (R3H domain containing like) and PI15 (peptidase inhibitor 15). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Ag5r2 in Genome Data Viewer
    Location:
    12F4-12F4; 1-49 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (14782962..14784052, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (14676995..14678085, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45522 Neighboring gene Antigen 5-related Neighboring gene rutabaga

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sequence and expression of Drosophila Antigen 5-related 2, a new member of the CAP gene family. Megraw T, et al. Gene, 1998 Nov 19. PMID 9831665
    2. Transposable elements contribute to the genomic response to insecticides in Drosophila melanogaster. Salces-Ortiz J, et al. Philos Trans R Soc Lond B Biol Sci, 2020 Mar 30. PMID 32075557, Free PMC Article
    3. Impaired peroxisomal import in Drosophila oenocytes causes cardiac dysfunction by inducing upd3 as a peroxikine. Huang K, et al. Nat Commun, 2020 Jun 10. PMID 32523050, Free PMC Article
    4. Proteasome stress in skeletal muscle mounts a long-range protective response that delays retinal and brain aging. Rai M, et al. Cell Metab, 2021 Jun 1. PMID 33773104, Free PMC Article
    5. Characterization of the SCP/TAPS gene family in Drosophila melanogaster. Kovalick GE, et al. Insect Biochem Mol Biol, 2005 Aug. PMID 15944079

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in multicellular organismal reproductive process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    antigen 5-related 2
    Names
    Ag5r2-PA
    CG9540-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      14782962..14784052 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_079950.4 → NP_524689.2  antigen 5-related 2 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_524689.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      O76553, Q9VY19
      Related
      FBpp0073755
      Conserved Domains (1) summary
      cd05380
      Location:62 → 211
      SCP_euk; SCP_euk: SCP-like extracellular protein domain, as found mainly in eukaryotes. This family includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5 from vespid venom. It has been proposed ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O76553 O76553
    Q9VY19 Q9VY19

    Gene LinkOut

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