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    Bem46 Bem46 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 44441, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Bem46provided by FlyBase
    Official Full Name
    Bem46provided by FlyBase
    Primary source
    FLYBASE:FBgn0025109
    Locus tag
    Dmel_CG18642
    See related
    AllianceGenome:FB:FBgn0025109
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    c1.6; CG18642; Dmel\CG18642
    Summary
    Predicted to enable palmitoyl-(protein) hydrolase activity. Predicted to be involved in lipid metabolic process. Predicted to be active in membrane. Is expressed in adult head. Orthologous to human ABHD13 (abhydrolase domain containing 13). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Bem46 in Genome Data Viewer
    Location:
    23C4-23C4; 2-8 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (2988116..2990075)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (2988116..2990075)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Chromodomain-helicase-DNA-binding protein 1 Neighboring gene okra Neighboring gene uncharacterized protein Neighboring gene Ccdc85

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. okra and spindle-B encode components of the RAD52 DNA repair pathway and affect meiosis and patterning in Drosophila oogenesis. Ghabrial A, et al. Genes Dev, 1998 Sep 1. PMID 9732269, Free PMC Article
    2. Evidence for large domains of similarly expressed genes in the Drosophila genome. Spellman PT, et al. J Biol, 2002. PMID 12144710, Free PMC Article
    3. gammaTub23C interacts genetically with brahma chromatin-remodeling complexes in Drosophila melanogaster. Vázquez M, et al. Genetics, 2008 Oct. PMID 18780727, Free PMC Article
    4. A Superfamily-wide Activity Atlas of Serine Hydrolases in Drosophila melanogaster. Kumar K, et al. Biochemistry, 2021 Apr 27. PMID 33827210, Free PMC Article
    5. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables palmitoyl-(protein) hydrolase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Bem46
    Names
    Bem46-PA
    CG18642-PA
    NP_477372.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      2988116..2990075
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058024.4 → NP_477372.1  Bem46 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_477372.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O76462
      Related
      FBpp0077328
      Conserved Domains (2) summary
      COG1073
      Location:72 → 305
      FrsA; Fermentation-respiration switch protein FrsA, has esterase activity, DUF1100 family [Signal transduction mechanisms]
      pfam12695
      Location:110 → 294
      Abhydrolase_5; Alpha/beta hydrolase family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O76461 O76461
    O76462 O76462

    Gene LinkOut

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