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    Vajk1 Vajk1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34809, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Vajk1provided by FlyBase
    Official Full Name
    Vajk1provided by FlyBase
    Primary source
    FLYBASE:FBgn0028938
    Locus tag
    Dmel_CG16886
    See related
    AllianceGenome:FB:FBgn0028938
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BG:DS00180.2; CG16886; Dmel\CG16886; vajk-1
    Summary
    Enables chitin binding activity. A structural constituent of chitin-based cuticle. Involved in chitin-based cuticle development. Located in chitin-based extracellular matrix. Is expressed in adult head; dorsal ectoderm anlage; and organism. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Vajk1 in Genome Data Viewer
    Location:
    34E4-34E4; 2-50 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (13920707..13923553, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (13920707..13923553, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Ance-2 Neighboring gene Acylphosphatase Neighboring gene Ance-3 Neighboring gene uncharacterized protein Neighboring gene Vajk2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genes encoding cuticular proteins are components of the Nimrod gene cluster in Drosophila. Cinege G, et al. Insect Biochem Mol Biol, 2017 Aug. PMID 28633893
    2. Functional conservation of the active sites of human and Drosophila angiotensin I-converting enzyme. Coates D, et al. Biochemistry, 2000 Aug 1. PMID 10913309
    3. A conserved gene cluster as a putative functional unit in insect innate immunity. Somogyi K, et al. FEBS Lett, 2010 Nov 5. PMID 20951134
    4. Spaceflight-related suboptimal conditions can accentuate the altered gravity response of Drosophila transcriptome. Herranz R, et al. Mol Ecol, 2010 Oct. PMID 20819157
    5. Regulators of Long-Term Memory Revealed by Mushroom Body-Specific Gene Expression Profiling in Drosophila melanogaster. Widmer YF, et al. Genetics, 2018 Aug. PMID 29925565, Free PMC Article

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Transcriptome profiling in the mushroom body-a memory center in the fly, identifies vajk-1 and hacd1 as learning and memory genes.
      Title: Regulators of Long-Term Memory Revealed by Mushroom Body-Specific Gene Expression Profiling in Drosophila melanogaster.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables chitin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables chitin binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of chitin-based cuticle IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chitin-based cuticle development IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in chitin-based cuticle development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in chitin-based extracellular matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in chitin-based extracellular matrix IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Vajk1
    Names
    CG16886-PA
    CG16886-PB
    Vajk1-PA
    Vajk1-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      13920707..13923553 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001201871.2 → NP_001188800.1  Vajk1, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001188800.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9MSI3

    2. NM_135844.4 → NP_609688.3  Vajk1, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609688.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9V3G8
      Related
      FBpp0080137
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9MSI3 M9MSI3
    Q9V3G8 Q9V3G8

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