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    Chrac-16 Chromatin accessibility complex 16kD protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32166, updated on 27-Dec-2024

    Summary

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    Official Symbol
    Chrac-16provided by FlyBase
    Official Full Name
    Chromatin accessibility complex 16kD proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0043001
    Locus tag
    Dmel_CG15736
    See related
    AllianceGenome:FB:FBgn0043001
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    15736; 20K protein; BcDNA:RE59557; CG15736; CHRAC; CHRAC-16; Chrac16; CHRAC16; Dmel\CG15736; joey
    Summary
    Predicted to enable protein heterodimerization activity. Involved in chromatin remodeling. Part of CHRAC. Is expressed in several structures, including embryonic brain; head mesoderm; optic lobe neuroepithelial cell; somatic muscle primordium; and ventral nerve cord. Orthologous to human CHRAC1 (chromatin accessibility complex subunit 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Chrac-16 in Genome Data Viewer
    Location:
    11A1-11A1; 1-38 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (12017225..12017961, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (11911258..11911994, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene furrowed Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene regucalcin Neighboring gene LSM12 homolog a Neighboring gene Transport and Golgi organization 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The histone fold subunits of Drosophila CHRAC facilitate nucleosome sliding through dynamic DNA interactions. Hartlepp KF, et al. Mol Cell Biol, 2005 Nov. PMID 16260604, Free PMC Article
    2. The DNA chaperone HMGB1 facilitates ACF/CHRAC-dependent nucleosome sliding. Bonaldi T, et al. EMBO J, 2002 Dec 16. PMID 12486007, Free PMC Article
    3. A role for tuned levels of nucleosome remodeler subunit ACF1 during Drosophila oogenesis. Börner K, et al. Dev Biol, 2016 Mar 15. PMID 26851213, Free PMC Article
    4. Chromatin-remodelling factor CHRAC contains the ATPases ISWI and topoisomerase II. Varga-Weisz PD, et al. Nature, 1997 Aug 7. PMID 9252192
    5. Acf1, the largest subunit of CHRAC, regulates ISWI-induced nucleosome remodelling. Eberharter A, et al. EMBO J, 2001 Jul 16. PMID 11447119, Free PMC Article

    See all (53) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. X-ray crystallographic structure of Drosophila melanogaster CHRAC14-CHRAC16 dimer
      Title: The histone fold subunits of Drosophila CHRAC facilitate nucleosome sliding through dynamic DNA interactions.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables protein heterodimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA-templated DNA replication IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in chromatin remodeling IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in chromatin remodeling IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of CHRAC IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of CHRAC IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    chromatin accessibility complex 16kD protein
    Names
    CG15736-PA
    CG15736-PB
    Chrac-16-PA
    Chrac-16-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      12017225..12017961 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298219.1 → NP_001285148.1  chromatin accessibility complex 16kD protein, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285148.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9V452
      Conserved Domains (1) summary
      pfam00808
      Location:18 → 83
      CBFD_NFYB_HMF; Histone-like transcription factor (CBF/NF-Y) and archaeal histone

    2. NM_132548.3 → NP_572776.1  chromatin accessibility complex 16kD protein, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572776.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9V452
      Related
      FBpp0073475
      Conserved Domains (1) summary
      pfam00808
      Location:18 → 83
      CBFD_NFYB_HMF; Histone-like transcription factor (CBF/NF-Y) and archaeal histone
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9V452.1 Q9V452

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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