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    Cyp311a1 Cytochrome P450 311a1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32170, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Cyp311a1provided by FlyBase
    Official Full Name
    Cytochrome P450 311a1provided by FlyBase
    Primary source
    FLYBASE:FBgn0030367
    Locus tag
    Dmel_CG1488
    See related
    AllianceGenome:FB:FBgn0030367
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    311a1; CG1488; CYP311A1; Dmel\CG1488
    Summary
    Predicted to enable several functions, including heme binding activity; iron ion binding activity; and monooxygenase activity. Is expressed in adult head and embryonic/larval midgut. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Cyp311a1 in Genome Data Viewer
    Location:
    11A2-11A2; 1-38 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (12029754..12031465, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (11923787..11925498, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR43960 Neighboring gene Transport and Golgi organization 4 Neighboring gene Cytochrome P450 318a1 Neighboring gene Ubiquitin-specific protease 7 Neighboring gene Tenascin accessory Neighboring gene Uch-L5-related

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. CYP311A1 in the anterior midgut is involved in lipid distribution and microvillus integrity in Drosophila melanogaster. Dong W, et al. Cell Mol Life Sci, 2022 Apr 28. PMID 35478270, Free PMC Article
    2. Role of CYP311A1 in wing development of Drosophila melanogaster. Zhang X, et al. Insect Sci, 2024 Jun. PMID 38445520
    3. Metabolic activation and toxicological evaluation of polychlorinated biphenyls in Drosophila melanogaster. Idda T, et al. Sci Rep, 2020 Dec 9. PMID 33299007, Free PMC Article
    4. Structural Modeling of Drosophila melanogaster Gut Cytochrome P450s and Docking Comparison of Fruit Fly Gut and Human Cytochrome P450s. Nirusimhan V, et al. Curr Drug Metab, 2022. PMID 35546755
    5. The molecular evolution of cytochrome P450 genes within and between drosophila species. Good RT, et al. Genome Biol Evol, 2014 Apr 20. PMID 24751979, Free PMC Article

    See all (35) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Role of CYP311A1 in wing development of Drosophila melanogaster.
      Title: Role of CYP311A1 in wing development of Drosophila melanogaster.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables monooxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    cytochrome P450 311a1
    Names
    CG1488-PB
    Cyp311a1-PB
    cytochrome P450
    NP_572780.3

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      12029754..12031465 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_132552.3 → NP_572780.3  cytochrome P450 311a1 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572780.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8SX16, Q9VYQ7
      Related
      FBpp0073473
      Conserved Domains (1) summary
      pfam00067
      Location:30 → 480
      p450; Cytochrome P450
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VYQ7.1 Q9VYQ7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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