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    Ripalpha RPA-interacting protein alpha [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34351, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ripalphaprovided by FlyBase
    Official Full Name
    RPA-interacting protein alphaprovided by FlyBase
    Primary source
    FLYBASE:FBgn0032189
    Locus tag
    Dmel_CG18145
    See related
    AllianceGenome:FB:FBgn0032189
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG18145; Dmel\CG18145; dRIPalpha; Tes83
    Summary
    Predicted to be involved in protein import into nucleus. Predicted to be active in nucleus. Is expressed in organism. Orthologous to human RPAIN (RPA interacting protein). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Ripalpha in Genome Data Viewer
    Location:
    31B1-31B1; 2-40 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (10199401..10200974, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (10199401..10200974, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Sulfonylurea receptor Neighboring gene Fumarase 4 Neighboring gene uncharacterized protein Neighboring gene Ribosomal protein L7

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Species-specific variation of RPA-interacting protein (RIP) splice isoforms. Kim K, et al. BMB Rep, 2009 Jan 31. PMID 19192389
    2. Transcription of histone gene cluster by differential core-promoter factors. Isogai Y, et al. Genes Dev, 2007 Nov 15. PMID 17978101, Free PMC Article
    3. Rapidly evolving genes of Drosophila: differing levels of selective pressure in testis, ovary, and head tissues between sibling species. Jagadeeshan S, et al. Mol Biol Evol, 2005 Sep. PMID 15917496
    4. Ultrasensitive proteome analysis using paramagnetic bead technology. Hughes CS, et al. Mol Syst Biol, 2014 Oct 30. PMID 25358341, Free PMC Article
    5. Spotted-dick, a zinc-finger protein of Drosophila required for expression of Orc4 and S phase. Page AR, et al. EMBO J, 2005 Dec 21. PMID 16369566, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The alternative splicing of RIPalpha in the Drosophila, Xenopus, and mouse system, was examined.
      Title: Species-specific variation of RPA-interacting protein (RIP) splice isoforms.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein import into nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    RPA-interacting protein alpha
    Names
    CG18145-PA
    Ripalpha-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      10199401..10200974 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135507.3 → NP_609351.1  RPA-interacting protein alpha [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609351.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q4PKP8, Q9VL31
      Related
      FBpp0079552
      Conserved Domains (1) summary
      pfam14768
      Location:122 → 196
      RPA_interact_C; Replication protein A interacting C-terminal
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VL31.1 Q9VL31

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
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