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    CG13436 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37334, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG13436provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034532
    Locus tag
    Dmel_CG13436
    See related
    AllianceGenome:FB:FBgn0034532
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG13436
    Summary
    Predicted to be involved in regulation of cilium beat frequency. Predicted to be active in axoneme and ciliary basal body. Is expressed in spermatozoon. Orthologous to human CFAP206 (cilia and flagella associated protein 206). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG13436 in Genome Data Viewer
    Location:
    57A8-57A8; 2-91 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (20636392..20638423)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (16523897..16525928)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Family with sequence similarity 21 Neighboring gene Reduction in Cnn dots 6 Neighboring gene rigor mortis Neighboring gene maf-S Neighboring gene uncharacterized protein Neighboring gene RNA polymerase III subunit K Neighboring gene Threonyl-carbamoyl synthesis 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A genome-scale protein interaction profile of Drosophila p53 uncovers additional nodes of the human p53 network. Lunardi A, et al. Proc Natl Acad Sci U S A, 2010 Apr 6. PMID 20308539, Free PMC Article
    2. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article
    3. mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster. Lepennetier G, et al. G3 (Bethesda), 2016 Jun 1. PMID 27172210, Free PMC Article
    4. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article
    5. A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. Neely GG, et al. Cell, 2010 Apr 2. PMID 20371351, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in regulation of cilium beat frequency IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in axoneme IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in ciliary basal body IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG13436-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      20636392..20638423
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137654.1 → NP_611498.1  uncharacterized protein Dmel_CG13436 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611498.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1ZBX0, Q8T4E2
      Related
      FBpp0085543, FBtr0086229
      Conserved Domains (1) summary
      pfam12018
      Location:219 → 491
      DUF3508; Domain of unknown function (DUF3508)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1ZBX0 A1ZBX0
    Q8T4E2 Q8T4E2

    Gene LinkOut

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