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    ppk9 pickpocket 9 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37498, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ppk9provided by FlyBase
    Official Full Name
    pickpocket 9provided by FlyBase
    Primary source
    FLYBASE:FBgn0085398
    Locus tag
    Dmel_CG34369
    See related
    AllianceGenome:FB:FBgn0085398
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG13489; CG13490; CG34369; Dmel\CG34369
    Old locus tag
    CG13489; CG13490; Dmel_CG13489; Dmel_CG13490
    Summary
    Predicted to enable ligand-gated sodium channel activity. Predicted to be involved in sodium ion transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See ppk9 in Genome Data Viewer
    Location:
    58A4-58A4; 2-97 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (21964173..21970664)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (17851678..17858169)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sensory functions for degenerin/epithelial sodium channels (DEG/ENaC). Ben-Shahar Y. Adv Genet, 2011. PMID 22099690, Free PMC Article
    2. Evolution of the Insect PPK Gene Family. Latorre-Estivalis JM, et al. Genome Biol Evol, 2021 Sep 1. PMID 34390578, Free PMC Article
    3. The genetic architecture of degenerin/epithelial sodium channels in Drosophila. Zelle KM, et al. G3 (Bethesda), 2013 Mar. PMID 23449991, Free PMC Article
    4. SCORE: a computational approach to the identification of cis-regulatory modules and target genes in whole-genome sequence data. Site clustering over random expectation. Rebeiz M, et al. Proc Natl Acad Sci U S A, 2002 Jul 23. PMID 12107285, Free PMC Article
    5. Molecular and cellular basis of sodium sensing in Drosophila labellum. Asefa WR, et al. iScience, 2024 Jul 19. PMID 39015148, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ligand-gated sodium channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables sodium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sodium channel activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in sodium ion transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in sodium ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in sodium ion transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    pickpocket 9
    Names
    CG34369-PA
    CG34369-PB
    ppk9-PA
    ppk9-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      21964173..21970664
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001299771.1 → NP_001286700.1  pickpocket 9, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286700.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4LG42
      Conserved Domains (1) summary
      pfam00858
      Location:154 → 579
      ASC; Amiloride-sensitive sodium channel

    2. NM_137778.2 → NP_611622.2  pickpocket 9, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611622.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W2B5
      Conserved Domains (1) summary
      pfam00858
      Location:154 → 587
      ASC; Amiloride-sensitive sodium channel
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4LG42 A0A0B4LG42
    Q9W2B5 Q9W2B5

    Gene LinkOut

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