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    dany distal antenna-young [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 246593, updated on 9-Dec-2024

    Summary

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    Official Symbol
    danyprovided by FlyBase
    Official Full Name
    distal antenna-youngprovided by FlyBase
    Primary source
    FLYBASE:FBgn0050401
    Locus tag
    Dmel_CG30401
    See related
    AllianceGenome:FB:FBgn0050401
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG13496; CG30401; Dmel\CG30401
    Summary
    Predicted to enable DNA binding activity. Involved in regulation of transcription by RNA polymerase II. Located in nucleolus and polytene chromosome interband. Is expressed in several structures, including germarium region 1; germarium region 2a; germarium region 2b; germarium region 3; and germline cell. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See dany in Genome Data Viewer
    Location:
    58B1-58B1; 2-98 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (21985626..21986938, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (17873131..17874443, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Gustatory receptor 58b Neighboring gene Gustatory receptor 58a Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Protein phosphatase D5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. An autoregulatory switch in sex-specific phf7 transcription causes loss of sexual identity and tumors in the Drosophila female germline. Smolko AE, et al. Development, 2020 Sep 11. PMID 32816970, Free PMC Article
    2. Early development of Drosophila embryos requires Smc5/6 function during oogenesis. Tran M, et al. Biol Open, 2016 Jul 15. PMID 27288507, Free PMC Article
    3. Drosophila dany is essential for transcriptional control and nuclear architecture in spermatocytes. Trost M, et al. Development, 2016 Jul 15. PMID 27436041
    4. How do Wolbachia modify the Drosophila ovary? New evidences support the "titration-restitution" model for the mechanisms of Wolbachia-induced CI. He Z, et al. BMC Genomics, 2019 Jul 24. PMID 31340757, Free PMC Article
    5. The Drosophila Pipsqueak protein defines a new family of helix-turn-helix DNA-binding proteins. Siegmund T, et al. Dev Genes Evol, 2002 Apr. PMID 11976954

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Dany is essential for the coordination of change in cell type-specific expression programs and large-scale spatial chromatin reorganization.
      Title: Drosophila dany is essential for transcriptional control and nuclear architecture in spermatocytes.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleolus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in polytene chromosome interband IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    distal antenna-young
    Names
    CG30401-PA
    CG30401-PC
    dany-PA
    dany-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      21985626..21986938 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_166493.2 → NP_726137.2  distal antenna-young, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_726137.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      E0R921, Q9W2B0
      Conserved Domains (2) summary
      TIGR02937
      Location:17 → 62
      sigma70-ECF; RNA polymerase sigma factor, sigma-70 family
      cl21459
      Location:10 → 60
      HTH; Helix-turn-helix domains

    2. NM_166494.3 → NP_726138.1  distal antenna-young, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_726138.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E0R921, Q9W2B0
      Related
      FBpp0071647
      Conserved Domains (2) summary
      TIGR02937
      Location:17 → 62
      sigma70-ECF; RNA polymerase sigma factor, sigma-70 family
      cl21459
      Location:10 → 60
      HTH; Helix-turn-helix domains
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W2B0 Q9W2B0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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