Sf3b3 Splicing factor 3b subunit 3 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Sf3b3provided by FlyBase
Official Full Name: Splicing factor 3b subunit 3provided by FlyBase
Primary source: FLYBASE:FBgn0035162
Locus tag: Dmel_CG13900
See related: AllianceGenome:FB:FBgn0035162
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG13900; Dmel\CG13900; SF3B3
Summary: Predicted to enable U2 snRNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Part of SAGA complex and U2 snRNP. Is expressed in several structures, including adult head; anterior endoderm; embryonic/larval midgut primordium; gut section; and mesoderm. Orthologous to human SF3B3 (splicing factor 3b subunit 3). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3L	NT_037436.4 (826720..833385, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3L	NT_037436.3 (826720..833385, complement)

Chromosome 3L - NT_037436.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables U2 snRNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in mRNA splicing, via spliceosome	IBA Inferred from Biological aspect of Ancestor more info
involved_in mRNA splicing, via spliceosome	IC Inferred by Curator more info	PubMed
involved_in mRNA splicing, via spliceosome	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Component	Evidence Code	Pubs
part_of SAGA complex	IDA Inferred from Direct Assay more info	PubMed
part_of U2 snRNP	IBA Inferred from Biological aspect of Ancestor more info
part_of U2 snRNP	IDA Inferred from Direct Assay more info	PubMed
part_of U2 snRNP	ISS Inferred from Sequence or Structural Similarity more info	PubMed
part_of catalytic step 2 spliceosome	HDA more info	PubMed
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of precatalytic spliceosome	HDA more info	PubMed
part_of small nuclear ribonucleoprotein complex	ISS Inferred from Sequence or Structural Similarity more info	PubMed

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The following sections contain reference sequences that belong to a specific genome build. Explain