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    AttD Attacin-D [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42122, updated on 9-Dec-2024

    Summary

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    Official Symbol
    AttDprovided by FlyBase
    Official Full Name
    Attacin-Dprovided by FlyBase
    Primary source
    FLYBASE:FBgn0038530
    Locus tag
    Dmel_CG7629
    See related
    AllianceGenome:FB:FBgn0038530
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    att; Att; att D; Attacin D; attacin-D; attD; ATTD; CG7629; Dmel\CG7629
    Summary
    Involved in defense response to Gram-positive bacterium and response to wounding. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See AttD in Genome Data Viewer
    Location:
    90B6-90B6; 3-61 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (17625268..17626086)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (13450990..13451808)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene transfer RNA:Threonine-AGT 1-5 Neighboring gene transfer RNA:Threonine-AGT 1-6 Neighboring gene uncharacterized protein Neighboring gene transfer RNA:Valine-AAC 1-2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Intruding Wolbachia Strain from the Moth Fails to Establish Itself in the Fruit Fly Due to Immune and Exclusion Reactions. Liu XC, et al. Curr Microbiol, 2020 Sep. PMID 32506239
    2. Defective phagocytosis leads to neurodegeneration through systemic increased innate immune signaling. Elguero JE, et al. iScience, 2023 Oct 20. PMID 37854687, Free PMC Article
    3. Dysregulation of antimicrobial peptide expression distinguishes Alzheimer's disease from normal aging. Wang M, et al. Aging (Albany NY), 2020 Jan 6. PMID 31907335, Free PMC Article
    4. Transmission of the wMel Wolbachia strain is modulated by its titre and by immune genes in Drosophila melanogaster (Wolbachia density and transmission). Liu XC, et al. J Invertebr Pathol, 2021 May. PMID 33882275
    5. Wolbachia-mediated antibacterial protection and immune gene regulation in Drosophila. Wong ZS, et al. PLoS One, 2011. PMID 21980455, Free PMC Article

    See all (187) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in defense response to Gram-positive bacterium IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in defense response to bacterium IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in response to wounding IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Attacin-D
    Names
    AttD-PA
    AttacinD
    CG7629-PA
    attacin
    attacin D
    attackin

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      17625268..17626086
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_079667.3 → NP_524391.2  Attacin-D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_524391.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9GPI2, Q9VEH5
      Related
      FBpp0082908
      Conserved Domains (2) summary
      pfam03768
      Location:1 → 65
      Attacin_N; Attacin, N-terminal region
      pfam03769
      Location:67 → 181
      Attacin_C; Attacin, C-terminal region
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9GPI2 Q9GPI2
    Q9VEH5 Q9VEH5

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
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