Snmp1 Sensory neuron membrane protein 1 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Snmp1provided by FlyBase
Official Full Name: Sensory neuron membrane protein 1provided by FlyBase
Primary source: FLYBASE:FBgn0260004
Locus tag: Dmel_CG7000
See related: AllianceGenome:FB:FBgn0260004
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG7000; Dmel\CG7000; snmp; Snmp; SNMP; snmp1; SNMP1
Summary: Predicted to enable scavenger receptor activity. Involved in several processes, including cellular response to pheromone; detection of chemical stimulus involved in sensory perception of smell; and pupariation. Located in cilium; dendrite; and neuronal cell body. Is expressed in several structures, including embryonic/larval fat body; gland; gonad; olfactory receptor neurons; and organism subdivision. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: 93C2-93C2; 3-71 cM

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (21165167..21168205, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (16990889..16993927, complement)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Snmp1 Microplitis mediator (Hymenoptera: Braconidae) orthologue (MmedSNMP1) was mainly expressed in sensilla placodea of antennae and possibly involved in perceiving plant volatiles and sex pheromones.
Title: Molecular characterization and expression of sensory neuron membrane proteins in the parasitoid Microplitis mediator (Hymenoptera: Braconidae).
SNMP1 funnels hydrophobic pheromones from the extracellular fluid to integral membrane receptors.
Title: A CD36 ectodomain mediates insect pheromone detection via a putative tunnelling mechanism.
Our results thus clarify SNMP1 as an important player required for the rapid kinetics of the pheromone response in insects.
Title: Requirement for Drosophila SNMP1 for rapid activation and termination of pheromone-induced activity.
results show highly regulated expression patterns, with three genes crq, pes and Snmp being upregulated in steroidogenic tissues at the onset of pupariation when steroidogenesis is crucial
Title: Expression of the Scavenger Receptor Class B type I (SR-BI) family in Drosophila melanogaster.
SNMP is a signaling component required for pheromone sensitivity in Drosophila.
Title: SNMP is a signaling component required for pheromone sensitivity in Drosophila.
a Drosophila melanogaster CD36 homologue, Sensory neuron membrane protein (SNMP), is expressed in a population of olfactory sensory neurons (OSNs) implicated in pheromone detection.
Title: An essential role for a CD36-related receptor in pheromone detection in Drosophila.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by FlyBase

Function	Evidence Code	Pubs
enables scavenger receptor activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in cell surface receptor signaling pathway	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in cellular response to pheromone	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in detection of chemical stimulus involved in sensory perception of smell	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in lipid homeostasis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in pupariation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to pheromone	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in cilium	IDA Inferred from Direct Assay more info	PubMed
located_in dendrite	IDA Inferred from Direct Assay more info	PubMed
is_active_in membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in neuronal cell body	IDA Inferred from Direct Assay more info	PubMed