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    CG5535 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39990, updated on 9-Dec-2024

    Summary

    Official Symbol
    CG5535provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036764
    Locus tag
    Dmel_CG5535
    See related
    AllianceGenome:FB:FBgn0036764
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0118547.111; Dmel\CG5535
    Summary
    Predicted to enable L-arginine transmembrane transporter activity; L-lysine transmembrane transporter activity; and L-ornithine transmembrane transporter activity. Predicted to be involved in L-arginine import across plasma membrane and L-ornithine transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including anterior-posterior subdivision of organism; dorsal pharyngeal muscle primordium; larval muscle cell; and visceral muscle primordium. Orthologous to human SLC7A1 (solute carrier family 7 member 1); SLC7A2 (solute carrier family 7 member 2); and SLC7A3 (solute carrier family 7 member 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See CG5535 in Genome Data Viewer
    Location:
    75A4-75A4; 3-45 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (17852624..17856794, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (17845724..17849894, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Tryptophanyl-tRNA synthetase, mitochondrial Neighboring gene uncharacterized protein Neighboring gene pseudo

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables L-arginine transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables L-lysine transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables L-ornithine transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables amino acid transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in L-arginine import across plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in L-ornithine transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in amino acid transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    uncharacterized protein
    Names
    CG5535-PB
    CG5535-PC

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      17852624..17856794 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140762.2NP_649019.2  uncharacterized protein Dmel_CG5535, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649019.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      B5RJ28, Q9VVL9, Q9VVM0
      Conserved Domains (2) summary
      TIGR00906
      Location:20585
      2A0303; cationic amino acid transport permease
      pfam13906
      Location:535585
      AA_permease_C; C-terminus of AA_permease
    2. NM_168753.1NP_730312.1  uncharacterized protein Dmel_CG5535, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_730312.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B5RJ28, Q7KUR6
      Related
      FBpp0074925, FBtr0075159
      Conserved Domains (2) summary
      TIGR00906
      Location:11576
      2A0303; cationic amino acid transport permease
      pfam13906
      Location:526576
      AA_permease_C; C-terminus of AA_permease