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    Polr1F RNA polymerase I subunit F [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33963, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Polr1Fprovided by FlyBase
    Official Full Name
    RNA polymerase I subunit Fprovided by FlyBase
    Primary source
    FLYBASE:FBgn0042092
    Locus tag
    Dmel_CG13773
    See related
    AllianceGenome:FB:FBgn0042092
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BEST:GH23590; CG13773; dA43; Dmel\CG13773; RPA43
    Summary
    Predicted to be involved in transcription elongation by RNA polymerase I. Predicted to be part of RNA polymerase I complex. Orthologous to human POLR1F (RNA polymerase I subunit F). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Polr1F in Genome Data Viewer
    Location:
    27C4-27C4; 2-23 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (6906666..6907844, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (6906666..6907844, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44914 Neighboring gene Neuroligin 2 Neighboring gene mir-932 stem loop Neighboring gene Rat1 5'-3' exoribonuclease Neighboring gene Wee1 kinase Neighboring gene uncharacterized protein Neighboring gene x16 splicing factor

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Drosophila neuroligin 2 is required presynaptically and postsynaptically for proper synaptic differentiation and synaptic transmission. Chen YC, et al. J Neurosci, 2012 Nov 7. PMID 23136438, Free PMC Article
    2. Partial Inhibition of RNA Polymerase I Promotes Animal Health and Longevity. Martínez Corrales G, et al. Cell Rep, 2020 Feb 11. PMID 32049000, Free PMC Article
    3. Drosophila wee1 has an essential role in the nuclear divisions of early embryogenesis. Price D, et al. Genetics, 2000 May. PMID 10790391, Free PMC Article
    4. Repression of interrupted and intact rDNA by the SUMO pathway in Drosophila melanogaster. Luo Y, et al. Elife, 2020 Nov 9. PMID 33164748, Free PMC Article
    5. In silico identification of Drosophila melanogaster genes encoding RNA polymerase subunits. Marygold SJ, et al. MicroPubl Biol, 2020 Oct 20. PMID 33274328, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in DNA-templated transcription initiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transcription by RNA polymerase I ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in transcription elongation by RNA polymerase I IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of RNA polymerase I complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of RNA polymerase I complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    RNA polymerase I subunit F
    Names
    CG13773-PA
    Polr1F-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      6906666..6907844 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135237.3 → NP_609081.1  RNA polymerase I subunit F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609081.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VM72
      Related
      FBpp0079000
      Conserved Domains (1) summary
      cd04328
      Location:19 → 107
      RNAP_I_Rpa43_N; RNAP_I_Rpa43_N: Rpa43, N-terminal ribonucleoprotein (RNP) domain. Rpa43 is a subunit of eukaryotic RNA polymerase (RNAP) I that is homologous to Rpb7 of eukaryotic RNAP II, Rpc25 of eukaryotic RNP III, and RpoE of archaeal RNAP. Rpa43 has two domains, an ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VM72 Q9VM72

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