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    CG8478 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41194, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG8478provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037746
    Locus tag
    Dmel_CG8478
    See related
    AllianceGenome:FB:FBgn0037746
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG8478
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in several structures, including antennal primordium; anterior endoderm; head epidermis primordium; mesoderm; and ventral nerve cord. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG8478 in Genome Data Viewer
    Location:
    85E7-85E8; 3-49 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (9763650..9766135)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (5589372..5591857)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Mannose phosphate isomerase Neighboring gene Synaptosomal-associated protein 24kDa Neighboring gene Mediator complex subunit 6 Neighboring gene N(alpha)-acetyltransferase 80 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Novel perspectives of target-binding by the evolutionarily conserved PP4 phosphatase. Karman Z, et al. Open Biol, 2020 Dec. PMID 33352067, Free PMC Article
    2. Comparative analysis of regulatory information and circuits across distant species. Boyle AP, et al. Nature, 2014 Aug 28. PMID 25164757, Free PMC Article
    3. Diverse patterns of genomic targeting by transcriptional regulators in Drosophila melanogaster. Slattery M, et al. Genome Res, 2014 Jul. PMID 24985916, Free PMC Article
    4. Transcriptional control in embryonic Drosophila midline guidance assessed through a whole genome approach. Magalhães TR, et al. BMC Neurosci, 2007 Jul 31. PMID 17672901, Free PMC Article
    5. Single-cell sequencing of tumor-associated macrophages in a Drosophila model. Khalili D, et al. Front Immunol, 2023. PMID 37795097, Free PMC Article

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG8478-PB
    CG8478-PC
    CG8478-PD
    CG8478-PE

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      9763650..9766135
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141684.4 → NP_649941.3  uncharacterized protein Dmel_CG8478, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649941.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q6NN19, Q8INN1, Q961C3
      Conserved Domains (2) summary
      sd00017
      Location:374 → 394
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:372 → 394
      zf-C2H2; Zinc finger, C2H2 type

    2. NM_001170105.2 → NP_001163576.1  uncharacterized protein Dmel_CG8478, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001163576.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E1JIH4, Q6NN19
      Conserved Domains (2) summary
      sd00017
      Location:379 → 399
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:377 → 399
      zf-C2H2; Zinc finger, C2H2 type

    3. NM_169309.5 → NP_731402.3  uncharacterized protein Dmel_CG8478, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_731402.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q6NN19, Q9VH75
      Conserved Domains (2) summary
      sd00017
      Location:375 → 395
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:373 → 395
      zf-C2H2; Zinc finger, C2H2 type

    4. NM_001275505.1 → NP_001262434.1  uncharacterized protein Dmel_CG8478, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262434.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q6NN19, Q8INN1, Q961C3
      Conserved Domains (2) summary
      sd00017
      Location:374 → 394
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:372 → 394
      zf-C2H2; Zinc finger, C2H2 type
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    E1JIH4 E1JIH4
    Q961C3 Q961C3
    Q9VH75 Q9VH75

    Gene LinkOut

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