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    CG32260 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 317943, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG32260provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0052260
    Locus tag
    Dmel_CG32260
    See related
    AllianceGenome:FB:FBgn0052260
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:GH24648; cSP232; Dmel\CG32260
    Summary
    Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG32260 in Genome Data Viewer
    Location:
    64A7-64A8; 3-10 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (4142364..4145966)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (4142364..4145966)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Ras oncogene at 64B Neighboring gene Adipokinetic hormone Neighboring gene uncharacterized protein Neighboring gene nab

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Building a platform for predicting functions of serine protease-related proteins in Drosophila melanogaster and other insects. Cao X, et al. Insect Biochem Mol Biol, 2018 Dec. PMID 30367934, Free PMC Article
    2. A Superfamily-wide Activity Atlas of Serine Hydrolases in Drosophila melanogaster. Kumar K, et al. Biochemistry, 2021 Apr 27. PMID 33827210, Free PMC Article
    3. Genome-wide association analysis of oxidative stress resistance in Drosophila melanogaster. Weber AL, et al. PLoS One, 2012. PMID 22496853, Free PMC Article
    4. Phylostratigraphic bias creates spurious patterns of genome evolution. Moyers BA, et al. Mol Biol Evol, 2015 Jan. PMID 25312911, Free PMC Article
    5. A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. Neely GG, et al. Cell, 2010 Apr 2. PMID 20371351, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables serine-type endopeptidase activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG32260-PA
    CG32260-PC
    NP_001261405.1
    NP_728942.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      4142364..4145966
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001274476.1 → NP_001261405.1  uncharacterized protein Dmel_CG32260, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261405.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PE97
      Conserved Domains (3) summary
      smart00020
      Location:147 → 388
      Tryp_SPc; Trypsin-like serine protease
      cd00190
      Location:148 → 391
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
      pfam12032
      Location:14 → 64
      CLIP; Regulatory CLIP domain of proteinases

    2. NM_168065.2 → NP_728942.1  uncharacterized protein Dmel_CG32260, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_728942.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IRB8
      Related
      FBpp0073070
      Conserved Domains (3) summary
      smart00020
      Location:327 → 568
      Tryp_SPc; Trypsin-like serine protease
      cd00190
      Location:328 → 571
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
      pfam12032
      Location:194 → 244
      CLIP; Regulatory CLIP domain of proteinases
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9PE97 M9PE97
    Q8IH45 Q8IH45
    Q8IRB8 Q8IRB8

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